The effect of 16 weeks of resistance training with blood flow restriction on psychological and physical indicators, and quality of life in men with type 2 diabetes: A randomized controlled clinical trial study

Abbaszadeh bazzi, Negin; Nayebifar, Shila; Ghasemi, Elham; Karimkoshteh, Azra

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Research code: IR.USB.REC.1402.02

Ethics code: IR.USB.REC.1402.022

The effect of 16 weeks of resistance training with blood flow restriction on psychological and physical indicators, and quality of life in men with type 2 diabetes: A randomized controlled clinical trial study

Negin Abbaszadeh bazzi¹

, Shila Nayebifar ^*²

, Elham Ghasemi³

, Azra Karimkoshteh⁴

1- Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran
2- Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran , shila_nayebifar@ped.usb.ac.ir
3- Department of Sport Sciences, Faculty of Literature and Humanities, University of Zabol, Zabol, Iran
4- Adult Endocrinology and Metabolism Specialist, Department of Internal Medicine of Ali Ibn Abitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran

Abstract: (10 Views)

ackground and Aims: The psychological challenges of diabetes exacerbate clinical symptoms and reduce quality of life. The present study aimed to determine the effect of 16 weeks of resistance training with blood flow restriction on anxiety, stress, and depression levels, physical indicators, and quality of life in males with type 2 diabetes.
Materials and Methods: The present study was conducted on 45 men with type 2 diabetes who were selected through convenience sampling and randomly divided into three equal groups (15 cases each), namely traditional resistance training, resistance training with blood flow restriction, and control. Subjects in the traditional training group performed training at an intensity of 70%-80% of one repetition maximum (1RM), and the restricted group performed training at an intensity of 20%-30% of 1RM for 16 weeks. At the beginning and end of the study, the Depression, Anxiety, and Stress (DASS-21) and Quality of Life (SF-36) questionnaires were completed; moreover, upper and lower body strength were measured. Statistical analysis was performed using SPSS software (version 26) through paired t-tests, analysis of covariance, post hoc LSD, and Pearson correlation at a significance level of P≤0.05.
Results: The results indicated a significant decrease in stress levels (P=0.001), anxiety (P=0.001), and depression (P=0.001); and an increase in upper body strength (P=0.002), lower body strength (P=0.01), skeletal muscle mass (P=0.002), and quality of life (P=0.001) in the two training groups, compared to the scores at pre-test. However, no significant difference was observed in the mean of these indices between the two training groups (P>0.05).

Conclusion: Both traditional resistance training and resistance training with blood flow restriction effectively improve psychological symptoms and physical performance in men with type 2 diabetes.

Keywords: Blood flow restriction, Quality of life, Resistance training, Type 2 diabetes

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Type of Study: Original Article | Subject: Exercise Physiology
Received: 2025/06/19 | Accepted: 2025/08/30 | ePublished ahead of print: 2025/09/15