Volume 32, Issue 1 (Spring 2025)                   J Birjand Univ Med Sci. 2025, 32(1): 37-46 | Back to browse issues page

Research code: IR.BIRJAND.REC.1399.001
Ethics code: IR.BIRJAND.REC.1399.001


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mogharnasi M, Galdavi R, Dehghani K. Changes of plasma Adipolin levels and some body composition indices in overweight and obese young women following eight weeks of intense interval training. J Birjand Univ Med Sci. 2025; 32 (1) :37-46
URL: http://journal.bums.ac.ir/article-1-3498-en.html
1- Department of Sports Sciences, University of Birjand, Birjand, Iran , mogharnasi@birjand.ac.ir
2- Department of Physical Education, Farhangian University, Tehran, Iran
Abstract:   (321 Views)
Background and Aims: Adipolin is an anti-inflammatory adipokine that plays a role in insulin resistance. This study aimed to examine the changes in plasma levels of adipolin and some body composition indices in overweight and obese women following eight weeks of intense interval training.
Materials and Methods: This quasi-experimental and applied study was performed on 30 subjects who were purposefully selected and randomly divided into two experimental and control groups (n=15). The intense interval-training program consisted of running for four minutes at an intensity of 45-60% of maximum heart rate. The first training session was performed at 45% of maximum heart rate, and gradually the intensity of the training was increased by 5% each week. After reaching an intensity of 60% of the heart rate, it was maintained until the end. Blood sampling was performed after 12 h of fasting in two stages, before and after the test, and the research variables were measured. Data were analyzed in SPSS software (version 24). For intra- and inter-group changes, dependent t-test and independent t-test were used at a significance level of P≤0.05.
Results:  According to the independent t-test, the values ​​of adipolin, body mass index, body weight, and waist to hip ratio in the experimental group were significantly different from those in the control group (P<0.05). Moreover, according to the dependent t-test, the values ​​of adipolin increased significantly after eight weeks of training, but body weight, BMI, and WHR decreased significantly (P<0.05).
Conclusion: In conclusion, regarding the increase in adipolin and the decrease in some body composition indices, it is recommended that overweight and obese individuals use high-intensity interval training methods to prevent obesity-related diseases.
Full-Text [PDF 510 kb]   (121 Downloads)    
Type of Study: Original Article | Subject: Exercise Physiology
Received: 2025/02/9 | Accepted: 2025/04/8 | ePublished ahead of print: 2025/05/12 | ePublished: 2025/04/4

References
1. Heymsfield S B, Wadden TA. Mechanisms, pathophysiology, and management of obesity, N Engl J Med. 2017; 376(3): 254-66. DOI: 10.1056/NEJMra1514009. [DOI:10.1056/NEJMra1514009] [PMID]
2. Shrewsbury VA, Burrows T, Ho M, Jensen M, Garnett SP, Stewart L, et al. Update of the best practice dietetic management of overweight and obese children and adolescents: a systematic review protocol. JBI Database System Rev Implement Rep. 2018; 16(7), 1495-502. DOI: 10.11124/JBISRIR-2017-003603. [DOI:10.11124/JBISRIR-2017-003603] [PMID]
3. Moran CN, Barwell ND, Malkova D, Cleland SJ, McPhee I, Packard CJ, et al. Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors. Metabolism. 2011; 60(2); 206-14. DOI: 10.1016/j.metabol.2009.12.026. [DOI:10.1016/j.metabol.2009.12.026] [PMID] []
4. Ouchi N, ParkerJL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011 [DOI:10.1038/nri2921] [PMID] []
5. 11(2): 85-97. DOI: 10.1038/nri2921. Epub 2011 Jan 21. [DOI:10.1038/nri2921] [PMID] []
6. Proença AR, Sertié RA, Oliveira AC, Campaãa AB, Caminhotto RO, Chimin P, et al. New concepts in white adipose tissue physiology. Braz. J. Med. Biol. Res. 2014; 47(3): 192-205. DOI: 10.1590/1414-431X20132911. [DOI:10.1590/1414-431X20132911] [PMID] []
7. Enomoto T, Ohashi K, Shibata R, Higuchi A, Maruyama S, Izumiya Y, et al. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism. J Biol Chem. 2011; 286(40): 34552-8. DOI: 10.1074/jbc.M111.277319. [DOI:10.1074/jbc.M111.277319] [PMID] []
8. Wei Z, Peterson JM, Lei X, Cebotaru L, Wolfgang MJ, Baldeviano GC, et al. C1q/TNF- related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes. J Biol Chem. 2012; 287(13): 10301-15. DOI: 10.1074/jbc.M111.303651. [DOI:10.1074/jbc.M111.303651] [PMID] []
9. Tan BK, Lewandowski KC, O'Hare JP, Randeva HS. Insulin regulates the novel adipokine /CTRP12: In vivo and ex vivo effects. J Endocrinol. 2014; 221(1): 111-9. DOI: 10.1530/JOE-13-0537. [DOI:10.1530/JOE-13-0537] [PMID]
10. Maillard F, Pereira B, Boissea, N. Effect of highintensity interval training on total, abdominal and visceral fat mass: a meta-analysis.2018; Sports Med. 48(2): 269-88. DOI: 10.1007/s40279-017-0807-y. [DOI:10.1007/s40279-017-0807-y] [PMID]
11. Aydin S, Kuloglu T, Aydin S, Eren MN, Yilmaz M, Kalayci M, et al. Expression of adropin in rat brain, cerebellum, kidneys, heart, liver, and pancreas in streptozotocin-induced diabetes. Mol Cell Biochem. 2013; 380(1-2): 73-81. DOI: 10.1007/s11010-013-1660-4. [DOI:10.1007/s11010-013-1660-4] [PMID]
12. Motahari-Tabari N, Shirvani MA, Shirzad-e-Ahoodashty M, Yousefi-Abdolmaleki E, Teimourzadeh M. The effect of 8 weeks aerobic exercise on insulin resistance in type 2 diabetes: a randomized clinical trial. Glob J Health. Sci. 2014; 7(1): 115-21. DOI: 10.5539/gjhs.v7n1p115. [DOI:10.5539/gjhs.v7n1p115] [PMID] []
13. Bluher, M. Adipose tissue dysfunction contributes to obesity related metabolic diseases. Best Pract Res Clin Endocrinol Metab. 2013; 27(2), 163-77. DOI: 10.1016/j.beem.2013.02.005. [DOI:10.1016/j.beem.2013.02.005] [PMID]
14. Soori R, Asad M, Barahouei-Jamar Z, Rezaeian N. The effect of aerobic training on the serum level of adipolin and insulin resistance in overweight men. Feyz Med Sci J. 2016; 19(6): 495-503. http://feyz.kaums.ac.ir/article-1-2917-en.html. [Persian]
15. Galdavi R, Mogharnasi M, Nayebifar S. The effect of continuous training on plasma levels of adipolin, insulin sensitivity and body fat percent in overweight and obese women. Journal of Practical Studies of Biosciences in Sport. 2022; 10(21), 42-52. DOI.org/10.22077/jpsbs.2021.3955.1608. [Persian]
16. Omidi M, Vismoradi P. Comparison of High and Moderate Intensity Aerobic Exercise on Serum Adipulin Levels and Some Indicators of Metabolic Syndrome in Obese Women. Iranian Journal of Diabetes and Metabolism. 2022; 21 (6): 404-413. http://ijdld.tums.ac.ir/article-1-6100-en.html. [Persian]
17. Montazeri Najafabadi Z, Keshavar Saeed, Eftekhari Gheinani, Elham Marvi Mahnaz. The effect of 12 weeks of Pilates training on serum levels of Adipolin, glycosylated hemoglobin and some body composition indicators in women with type 2 diabetes. Iran J Obstet Gynecol Infertil. 2024; 27(2): 27-35. DOI: 10.22038/ijogi.2024.73196.5760. [Persian]
18. Zimorovat A , Moghtaderi F, Amiri M , Dehkordi H-R, Mohyadini M, Mohammadi M ,et al. Validity and Reproducibility of a Semiquantitative Multiple-Choice Food Frequency Questionnaire in Iranian Adults. Food Nutr Bull. 2022; 43(2): 171-88. Doi: 10.1177/03795721221078353. [DOI:10.1177/03795721221078353] [PMID]
19. Kang J, Rashti SL, Tranchina CP, Ratamess NA, Faigenbaum AD, Hoffman JR. Effect of preceding resistance exercise on metabolism during subsequent aerobic session. Eur J Appl Physiol. 2009; 107(1): 43-50. DOI:10.1007/s00421-009-1100-z. [DOI:10.1007/s00421-009-1100-z] [PMID]
20. Ramos JS, Dalleck LC, Tjonna AE, Beetham KS, Coombes JS. The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function: a systematic review and meta-analysis. Sports Med. 2015; 45(5): 679-92. DOI: 10.1007/s40279-015-0321-z. [DOI:10.1007/s40279-015-0321-z] [PMID]
21. Balducci S, Zanuso S, Nicolucci A, Fernando F, Cavallo S, Cardelli P, et al. Anti-inflammatory effect of exercise training in subjects with type. Nutr Metab Cardiovasc Dis. 2010; 20(8): 608-17. DOI: 10.1016/j.numecd.2009.04.015. [DOI:10.1016/j.numecd.2009.04.015] [PMID]
22. Vu V, Riddell M C, & Sweeney G. Circulating adiponectin and adiponectin receptor expression in skeletal muscle: effects of exercise. Diabetes Metab Res Rev. 2007; 23(8): 600-11. DOI: 10.1002/dmrr.778. [DOI:10.1002/dmrr.778] [PMID]
23. Abdel-lateif DM, El-Shaer SS. Association between changes in serum vaspin concentrations and changes of anthropometric and metabolic variables in obese subjects after weight reduction. J Am Sci. 2012; 8(4), 606-11. URL: https://www.jofamericanscience.org/journals/am-sci/am0804/081_8716am0804_606_611.pdf
24. Karajibani M, Montazerifar F, Dehghani K, Mogharnasi M, Mousavi Gilani S R, Dasheipour A. Effect of 10 weeks of speed and endurance exercise and a period of detraining on serum nesfatin-1, lipid profiles, body fat percentage and Body mass index in non-athlete healthy men. Journal of Practical Studies of Biosciences in Sport. 2020; 7(14): 129-140. DOI: 10.22077/jpsbs.2019.1161. [Persian]
25. Galdavi R, Mogharnasi M. Effect two training methods of endurance and resistance on Omentin-1 levels of plasma and factors related to obesity and overweight in obese girls. J Am Sci. 2016; 15 (2): 101-09 http://ijdld.tums.ac.ir/article-1-5329-en.html. [Persian]
26. Mogharnasi M, Taji Tabas A. The Effect of 10 Weeks of Endurance Training of Cycle Ergometer on Nesfatin-1 Levels and Insulin Resistance in Women with Type 2 Diabetes. JSB. 2016; 8(1): 95-107. [DOI:10.22059/jsb.2016.58244. [Persian]]
27. Jafari M, Mogharnasi M, Galdavi R. The Effect of 8 Weeks of Resistance Training and a Period of Short-Term Detraining on Plasma Levels of Chemerin and Body Composition in Overweight and Obese Females, SPMI.2017; 9(1): 9-20. sportrc.ir/article61463.html?lang=en. [Persian]
28. Jalali Z, Shabani R, Nazari M.Effects of concurrent resistance-endurance training on body composition, lipid profile and blood glucose homeostasis in obese girls: A clinical trial. Iranian Journal of Pediatric Nursing. 2018; 4(4): 24-34 URL: http://jpen.ir/article-1-278-en.html. [Persian]
29. Akbarpour M, Ebrahimzadeh Z. Effect of Spirulina supplementation and aerobic exercise on the level of cortisol and body composition in women with type 2 diabetes. Adv Life Sci.2019; 6(3): 116-124.‌ DOI: 10.62940/als.v6i3.779 . [Persian]
30. Vahidian-Rezazadeh M, Monfared A, Mogharnasi M. Interactive effects of exercise on bicycle ergometer and anti-inflammatory extract of nettle on some obesity-related inflammatory markers in overweight and obese women. Journal of Practical Studies of Biosciences in Sport. 2018; 6(11): 95-107. DOI:org/10.22077/jpsbs.2018.434.1166. [Persian]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Journal of Translational Medical Research

Designed & Developed by : Yektaweb