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Vahdatpoor H, Alizadeh A A, Shakerian S. The effect of ginger supplement on oxidative stress induced by overweight extrinsic exertion and overweight. Journals of Birjand University of Medical Sciences 2017; 24 (4) :282-290
URL: http://journal.bums.ac.ir/article-1-2260-en.html

Background and Aim: Many studies have shown that ginger has a strong antioxidant activity against free radical because of the presence of flavonoids, isoflavoneous and vaccine. Therefore, this study aimed to investigate the effect of short-term ginger supplementation on oxidative stress resulting from eccentric exercise in overweight girls.
Materials and Methods: In this quasi-experimental study, 22 overweight female students of were randomly divided into two groups, complementary (n=12) and placebo (n=10). Supplement group took 2 g of ginger supplement powder daily for two weeks. The exercise protocol included two exhaustive eccentric exercises (negative slope on a treadmill, one session before and one session after two weeks of supplementation) with an initial speed of 4 mph and the initial slope of negative 2% percent. To measure levels of malondialdehyde (MDA) and catalase (CAT) Blood samples were taken in 4 stages: before and immediately after training in two periods before and after the ginger consumption. To analyze data, t-test and analysis of covariance with Between-group factor was used.
Results: The results showed that eccentric exercise increases levels of MDA and decreases the amount of CAT (P≤0.05). Consumption of ginger supplement for two weeks also has a significant effect on reducing the MDA and increasing CAT (P≤‌0.05).
Conclusion: These results suggest that non-pharmacological approaches, such as ginger supplement with physical activity, may contribute to improving the quality of life and health of overweight people by reducing inflammation and cellular stress.