Volume 24, Issue 4 (January 2017)                   J Birjand Univ Med Sci 2017, 24(4): 243-253 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Danesh N M, Yousefi F, Nameghi M A, Abnous K, Taghdisi S M. Aptamers: Isolation, modification, characteristics, and applications . J Birjand Univ Med Sci. 2017; 24 (4) :243-253
URL: http://journal.bums.ac.ir/article-1-2382-en.html
1- Research Institute of Sciences and New Technology, Mashhad, Iran
2- MSc of Nursing, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
3- MSc, School of Pharmacy, Department of Medicinal Chemistry, Mashhad University of Medical Sciences, Mashhad, Iran
4- Professor, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
5- Assistant Professor, School of Pharmacy, Department of Pharmaceutical Biotechnology , Mashhad University of Medical Sciences, Mashhad, Iran , taghdisihm@mums.ac.ir
Abstract:   (7071 Views)
As synthetic oligonucleotides with high affinity and selectivity, aptamers have an outstanding potential for medical diagnosis and treatment. This manuscript enquires into the generation, characteristics and applications of aptamers. The role of aptamers in medicine is also discussed. The study shows that aptamers stand as great candidates in medical sciences for development of biosensors and targeted drug delivery systems because of their unique properties such as high affinity and selectivity towards their targets, inexpensiveness and in vitro synthesis, high stability, and small size.
Full-Text [PDF 688 kb]   (6443 Downloads)    
Type of Study: Review | Subject: Biotechnology
Received: 2017/12/9 | Accepted: 2018/01/21 | ePublished ahead of print: 2018/01/21 | ePublished: 2018/02/8

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | Journal of Birjand University of Medical Sciences

Designed & Developed by : Yektaweb