Volume 20, Issue 4 (Winter 2014)                   J Birjand Univ Med Sci. 2014, 20(4): 393-400 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Eizadi M, Kazemzade Y, Behbudi L, Banaeifar A. Determination of serum adiponectin relationship with insulin resistance in type 2 diabetics. J Birjand Univ Med Sci.. 2014; 20 (4) :393-400
URL: http://journal.bums.ac.ir/article-1-1249-en.html
1- in Physical Education and Sport Science, Saveh Branch, Islamic Azad University Saveh, Iran , izadimojtaba2006@yahoo.com
2- in Physical Education and Sport Science, Islamshahr Branch, Islamic Azad University Islamshahr, Iran.
3- in Physical Education and Sport Science, South Tehran Branch, Islamic Azad University Tehran, Iran.
Abstract:   (10531 Views)
Background and Aim: Obesity is associated with some chronic morbidity including atherosclerosis, hypertension, and type 2 diabetes which are major components of metabolic syndrome. In the present study, association between insulin resistance and adiponectin, as an anti-inflammatory cytokine, in type 2 obese male diabetics was assessed. Materials and Methods: In this descriptive study, fasting serum adiponectin, insulin, glucose and insulin resistance were measured in 42 obese male type 2 diabetics (aged 37 - 53 years, weight 80-100kg, 30≤BMI≤36). Pearson’s correlation method was used to determine the association between adiponectin levels with insulin resistance, glucose, and insulin in the cases (P≤0.05). Results: Pearson’s correlation method showed a significant negative association between serum adiponectin andinsulin resistance (P=0.000(. Besides, a significant correlation was observed between adiponectin level and fasting glucose (P=0.005). But, no correlation was found between serum adiponectin and insulin (P=0.196). Conclusion: The current study demonstrated that serum adiponectin level, as an anti-inflammation and anti-diabetic cytokine, is a predictive factor of insulin resistance in type 2 diabetics.
Full-Text [PDF 189 kb]   (3734 Downloads)    
Type of Study: Original Article | Subject: Physiology
Received: 2012/09/20 | Accepted: 2013/10/30 | ePublished: 2014/03/9

Add your comments about this article : Your username or Email:

Send email to the article author

© 2021 All Rights Reserved | Journal of Birjand University of Medical Sciences

Designed & Developed by : Yektaweb