Volume 18, Issue 4 (Winter 2011)                   J Birjand Univ Med Sci. 2011, 18(4): 285-292 | Back to browse issues page

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Eizadi M, Baghery G, Masroor H, Behboodi L, Dooaly H. The effect of long-term exercise on the secretion of serum Ghrelin in obese men. J Birjand Univ Med Sci.. 2011; 18 (4) :285-292
URL: http://journal.bums.ac.ir/article-1-853-en.html
1- Physical Education and Sport Science, Saveh Branch, Islamic Azad University, Iran , izadimojtaba2006@yahoo.com
2- Department of Physical Education and Sport Science, Tehran University, Qom college, Iran
3- Internist, Saveh Branch, Islamic Azad University, Iran.
4- Department of Physical Education and Sport Science, Islamshahr Branch, Islamic Azad University, Iran.
5- Physical Education and Sport Science, Saveh Branch, Islamic Azad University, Iran.
Abstract:   (15904 Views)
Background and Aim: Ghrelin, a 28-amino acid peptide, plays an important role in weight regulation and energy homeostasis. In this study, Ghrelin responses to a long-term aerobic exercise in obese men was studied. Materials and Methods: In this semi-experimental study, thirty adult obese males were randomly divided into a physically active (experimental) or a physically inactive (control) groups. Serum Ghrelin, lipid profile (TG, TC, LDL, HDL) and anthropometrical indexes were measured respectively before and after a 12 week aerobic exercise and detraining in the experimental and control groups. Blood samples were taken from all participants after an overnight fasting (12 hours). Statistical analysis was performed by means of SPSS software (version 15) using T-test method. Results: Aerobic exercise led to a significant decrease in serum Ghrelin and all anthropometrical indexes in the experimental group (P<0.05). In addition, TG concentration and ratio of TG to HDL decreased after aerobic exercise in the experimental group (P<0.05). All variables remained constant in the control group after detraining. Conclusion: The findings of the present study show that an exercise program, while significantly decreasing serum Ghrelin level, can be followed by weight loss and a decrease in fat tissues in obese men.
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Type of Study: Original Article | Subject: Physical Medicine and Rehabilitation
Received: 2011/05/21 | Accepted: 2011/11/9 | ePublished: 2016/03/10

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