Volume 30, Issue 4 (Januray 2024)
J Birjand Univ Med Sci. 2024, 30(4): 295-315 |
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Research code: 09153412696
Ethics code: 09153412696
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Mogharnasi M, Kazeminasab F, Zafarmand O, Hassanpour N. The effect of aerobic and resistance training on Omentin-1 and Nesfatin-1 levels in adults: A systematic review and meta -Analysis. Journals of Birjand University of Medical Sciences 2024; 30 (4) :295-315
URL: http://journal.bums.ac.ir/article-1-3359-en.html
URL: http://journal.bums.ac.ir/article-1-3359-en.html
1- Department of Sports Science, University of Birjand, Birjand, Iran , mogharnasi@birjand.ac.ir
2- Department of Physical Education and Sports Science, School of Humanities, University of Kashan, Kashan, Iran
3- Department of Physical Education and Sports Science, Faculty of Human Sciences, Yasouj University, Yasouj, Iran
2- Department of Physical Education and Sports Science, School of Humanities, University of Kashan, Kashan, Iran
3- Department of Physical Education and Sports Science, Faculty of Human Sciences, Yasouj University, Yasouj, Iran
Abstract: (925 Views)
Background and Aims: Adipokines omentin-1 and nesfatin-1 are hormones secreted from adipose tissue that effectively regulate metabolic pathways. On the other hand, exercise training plays a positive role in preventing metabolic diseases. The present study aimed to investigate the effect of aerobic and resistance training on the levels of omentin-1 and nesfatin-1 in adults.
Materials and Methods: A systematic search of English and Persian articles published in PubMed, Web of Science, SID, Scopus, and Magiran databases was conducted until September 2023. A meta-analysis was conducted to investigate the effect of aerobic and resistance training on the levels of omentin-1 and nesfatin-1 in adults. The mMean difference and 95% confidence interval (CI) were calculated using a random effect model. Heterogeneity was evaluated using the I2 test, and diffusion bias was evaluated by visual analysis of the funnel plot and Egger's test.
Results: In total, 26 studies, including 29 exercise interventions and 722 adults, 409 participants in the exercise group with an average age of 32.45 ± 3.71, and 313 participants in the control group with an average age of 29.86 ± 2.34 were added to the present meta-analysis. The results showed that exercise training caused a significant increase in omentin-1 [SMD=1.37, 0.83 to 1.91, P=0.001] and nesfatin-1 [SMD= 0.69, 0.01 to 1.37, P=0.04] compared to the control group in adults.
Conclusion: The results of the present study showed that both types of aerobic and resistance training lead to a significant increase in the levels of omentin-1 and nesfatin-1. It seems that exercise training can be a non-pharmacological and practical intervention to regulate adipokines in adults.
Materials and Methods: A systematic search of English and Persian articles published in PubMed, Web of Science, SID, Scopus, and Magiran databases was conducted until September 2023. A meta-analysis was conducted to investigate the effect of aerobic and resistance training on the levels of omentin-1 and nesfatin-1 in adults. The mMean difference and 95% confidence interval (CI) were calculated using a random effect model. Heterogeneity was evaluated using the I2 test, and diffusion bias was evaluated by visual analysis of the funnel plot and Egger's test.
Results: In total, 26 studies, including 29 exercise interventions and 722 adults, 409 participants in the exercise group with an average age of 32.45 ± 3.71, and 313 participants in the control group with an average age of 29.86 ± 2.34 were added to the present meta-analysis. The results showed that exercise training caused a significant increase in omentin-1 [SMD=1.37, 0.83 to 1.91, P=0.001] and nesfatin-1 [SMD= 0.69, 0.01 to 1.37, P=0.04] compared to the control group in adults.
Conclusion: The results of the present study showed that both types of aerobic and resistance training lead to a significant increase in the levels of omentin-1 and nesfatin-1. It seems that exercise training can be a non-pharmacological and practical intervention to regulate adipokines in adults.
*Corresponding Author: Mehdi Mogharnasi; Emails: mogharnasi@birjand.ac.ir
You can also search for this author in: PubMed ResearchGate Scopus Google Scholar Google Scholar Profile
Type of Study: Meta-analysis |
Subject:
Exercise Physiology
Received: 2023/12/4 | Accepted: 2024/01/29 | ePublished: 2024/02/4
Received: 2023/12/4 | Accepted: 2024/01/29 | ePublished: 2024/02/4
References
1. Li H, Hastings MH, Rosenzweig A. Exercise Training in Diabetes: Start Earlier or Exercise Harder. Circ Res. 2020;127(11):1401-3.
https://doi.org/10.1161/CIRCRESAHA.120.318219 [DOI:10.1161/circresaha.120.318219.] [PMID] []
2. Wright WS, Longo KA, Dolinsky VW, Gerin I, Kang S, Bennett CN, et al. Wnt10b inhibits obesity in ob/ob and agouti mice. Diabetes. 2007;56(2):295-303.
https://doi.org/10.2337/db06-1339 [DOI:10.2337/db06-1339.] [PMID]
3. Bai L, Wang Y, Fan J, Chen Y, Ji W, Qu A, et al. Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell Metab. 2007;5(1):47-57.
https://doi.org/10.1016/j.cmet.2006.11.013 [DOI:10.1016/j.cmet.2006.11.013.] [PMID]
4. Rotondi M, Magri F, Chiovato L. Thyroid and Obesity: Not a One-Way Interaction. J Clin Endocrinol Metab. 2011;96(2):344-6.
https://doi.org/10.1210/jc.2010-2515 [DOI:10.1210/jc.2010-2515.] [PMID]
5. Banitalebi E, Mardanpour Shahrekordi Z, Kazemi AR, Bagheri L, Amani Shalamzari S, Faramarzi M. Comparing the Effects of Eight Weeks of Combined Training (Endurance and Resistance) in Different Orders on Inflammatory Factors and Adipokines Among Elderly Females. Women's Health Bulletin. 2016;3(2):1-10.
https://doi.org/10.17795/whb-30990 [DOI:10.17795/whb-30990. [Persian].]
6. Yarahmadi H, Hamedinia M, Haghighi A, Jahandide A, Taher Z. The Effect of one session moderate and heavy resistance exercise on the appetite, food intake and energy expenditure in healthy men. Daneshvar (medicine) shahed University. 2010;18(89):1-11. https://daneshvarmed.shahed.ac.ir/article_1431.html?lang=en [Persian].
7. Taji Tabas A, Mogharnasi M. The eefect of 10 week resistance exercise training on werum levels of nesfatin-1 and insulin resistance index in women with type 2 diabetes. Iran J Endocrinol Metab. 2015; 14(3): 179-88. http://ijdld.tums.ac.ir/article-1-5367-en.html. [Persian].
8. Yang RZ, Lee MJ, Hu H, Pray J, Wu HB, Hansen BC, et al. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab. 2006;290(6):E1253-61.
https://doi.org/10.1152/ajpendo.00572.2004 [DOI:10.1152/ajpendo.00572.2004.] [PMID]
9. De Souza Batista CM, Yang RZ, Lee MJ, Glynn NM, Yu DZ, Pray J, et al. Omentin plasma levels and gene expression are decreased in obesity. Diabetes. 2007;56(6):1655-61.
https://doi.org/10.2337/db06-1506 [DOI:10.2337/db06-1506.] [PMID]
10. Safarzade A, Jafari M, Talebi-Garakani E. The Effect of 8 Weeks of Resistance Training on Plasma Omentin-1 Concentration and Insulin Resistance Index in Obese Men. Journal of Sport Biosciences. 2018;10(2):165-75. [DOI:10.22059/jsb.2018.114738.861. [Persian].]
11. Blüher M. Vaspin in obesity and diabetes: pathophysiological and clinical significance. Endocrine. 2012;41(2):176-82.
https://doi.org/10.1007/s12020-011-9572-0 [DOI:10.1007/s12020-011-9572-0.] [PMID]
12. Riyahi Malayeri S, Mirakhorli M. The Effect of 8 Weeks of Moderate Intensity Interval Training on Omentin Levels and Insulin Resistance Index in Obese Adolescent Girls. Sport Physiology & Management Investigations. 2018;10(2):59-68. https://www.sportrc.ir/article_67070.html?lang=en. [Persian].
13. Wilms B, Ernst B, Gerig R, Schultes B. Plasma omentin-1 levels are related to exercise performance in obese women and increase upon aerobic endurance training. Exp Clin Endocrinol Diabetes. 2015;123(3):187-92.
https://doi.org/10.1055/s-0034-1398504 [DOI:10.1055/s-0034-1398504.] [PMID]
14. Faramarzi M, Banitalebi E, Nori S, Farzin S, Taghavian Z. Effects of rhythmic aerobic exercise plus core stability training on serum omentin, chemerin and vaspin levels and insulin resistance of overweight women. J Sports Med Phys Fitness. 2016;56(4):476-82. https://pubmed.ncbi.nlm.nih.gov/25651894/.
15. Kaviyani-delshad G, Vesali-akbarpoor L, Samavati Sharif MA. Omentin-1 and chemerin's response to two different exercise models in overweight men. J adv biomed sci. 2019;9(1):1220-9. http://jabs.fums.ac.ir/article-1-1787-en.html. [Persian].
16. Galdavi R, Mogharnasi M. The effect of two methods of endurance and resistance training on omentin-1 levels of plasma and factors related to obesity in overweight and obese girls in university of sistan and bakuchestan. Iran J Endocrinol Metab. 2016; 15(2): 101-9. http://ijdld.tums.ac.ir/article-1-5329-en.html. [Persian].
17. Nakhaei K, Ghofrani M, Bakhsheshi MF, Nakhaei H. Effect of circuit resistance training and cinnamon supplement on body composition and Omentin-1 in overweight women. Iran J Obstet Gynecol Infertil. 2018;20(11):74-82. DOI: 10.22038/IJOGI.2018.10230. [Persian].
18. Asgari A, Niyazi A, Nejatian Hoseinpour A, Setayesh S, Fazolahzade Mousavi R, Mohammad Rahimi GR. The effect of exercise training on serum Omentin-1 levels, glycemic control and body composition in adults population: a systematic review and meta-analysis of randomized controlled trials. International Journal of Diabetes in Developing Countries. 2023.
https://doi.org/10.1007/s13410-023-01229-w [DOI:10.1007/s13410-023-01229-w.]
19. Kohno D, Nakata M, Maejima Y, Shimizu H, Sedbazar U, Yoshida N, et al. Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding. Endocrinology. 2008;149(3):1295-301.
https://doi.org/10.1210/en.2007-1276 [DOI:10.1210/en.2007-1276. [Persian].] [PMID]
20. Shimizu H, Ohsaki A, Oh IS, Okada S, Mori M. A new anorexigenic protein, nesfatin-1. Peptides. 2009;30(5):995-8.
https://doi.org/10.1016/j.peptides.2009.01.002 [DOI:10.1016/j.peptides.2009.01.002.] [PMID]
21. Ramanjaneya M, Chen J, Brown JE, Tripathi G, Hallschmid M, Patel S, et al. Identification of nesfatin-1 in human and murine adipose tissue: a novel depot-specific adipokine with increased levels in obesity. Endocrinology. 2010;151(7):3169-80.
https://doi.org/10.1210/en.2009-1358 [DOI:10.1210/en.2009-1358.] [PMID]
22. Shimizu H, Oh IS, Hashimoto K, Nakata M, Yamamoto S, Yoshida N, et al. Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism. Endocrinology. 2009;150(2):662-71.
https://doi.org/10.1210/en.2008-0598 [DOI:10.1210/en.2008-0598.] [PMID]
23. Babaei M, Abdi A, Mehrabani J, Abbassi Daloii A. The Effect of Aerobic Training and Spirulina on Nesfatin-1 and Peptide YY in Overweight Elderly Men: A randomized trial. Iranian Journal Of Health Sciences. 2022;10(2):48-57. http://jhs.mazums.ac.ir/article-1-799-en.html. [Persian]. [DOI:10.18502/jhs.v10i2.9767]
24. Amanat S, Sinaei E, Panji M, MohammadporHodki R, Bagheri-Hosseinabadi Z, Asadimehr H, et al. A Randomized Controlled Trial on the Effects of 12 Weeks of Aerobic, Resistance, and Combined Exercises Training on the Serum Levels of Nesfatin-1, Irisin-1 and HOMA-IR. Front Physiol. 2020;11:562895.
https://doi.org/10.3389/fphys.2020.562895 [DOI:10.3389/fphys.2020.562895.] [PMID] []
25. Mogharnasi M, TaheriChadorneshin H, Papoli-Baravati SA, Teymuri A. Effects of upper-body resistance exercise training on serum nesfatin-1 level, insulin resistance, and body composition in obese paraplegic men. Disabil Health J. 2019;12(1):29-34.
https://doi.org/10.1016/j.dhjo.2018.07.003 [DOI:10.1016/j.dhjo.2018.07.003.] [PMID]
26. Hwang CL, Lim J, Yoo JK, Kim HK, Hwang MH, Handberg EM, et al. Effect of all-extremity high-intensity interval training vs. moderate-intensity continuous training on aerobic fitness in middle-aged and older adults with type 2 diabetes: A randomized controlled trial. Exp Gerontol. 2019;116:46-53.
https://doi.org/10.1016/j.exger.2018.12.013 [DOI:10.1016/j.exger.2018.12.013.] [PMID] []
27. Li J, Cheng W, Ma H. A Comparative Study of Health Efficacy Indicators in Subjects with T2DM Applying Power Cycling to 12 Weeks of Low-Volume High-Intensity Interval Training and Moderate-Intensity Continuous Training. J Diabetes Res. 2022;2022:9273830.
https://doi.org/10.1155/2022/9273830 [DOI:10.1155/2022/9273830.] [PMID] []
28. Khalafi M, Malandish A, Rosenkranz SK, Ravasi AA. Effect of resistance training with and without caloric restriction on visceral fat: A systemic review and meta-analysis. Obes Rev. 2021;22(9):e13275.
https://doi.org/10.1111/obr.13275 [DOI:10.1111/obr.13275. [Persian].] [PMID]
29. Khalafi M, Alamdari KA, Symonds ME, Nobari H, Carlos-Vivas J. Impact of acute exercise on immediate and following early post-exercise FGF-21 concentration in adults: systematic review and meta-analysis. Hormones (Athens). 2021;20(1):23-33.
https://doi.org/10.1007/s42000-020-00245-3 [DOI:10.1007/s42000-020-00245-3. [Persian].] [PMID]
30. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. Bmj. 1997;315(7109):629-34.
https://doi.org/10.1136/bmj.315.7109.629 [DOI:10.1136/bmj.315.7109.629.] [PMID] []
31. Gao K, Su Z, Meng J, Yao Y, Li L, Su Y, et al. Effect of Exercise Training on Some Anti-Inflammatory Adipokines, High Sensitivity C-Reactive Protein, and Clinical Outcomes in Sedentary Adults With Metabolic Syndrome. Biol Res Nurs. 2024; 26(1): 125-138.
https://doi.org/10.1177/10998004231195541 [DOI:10.1177/10998004231195541.] [PMID]
32. Mousavi SM, Heidarianpour A, Tavassoli H. Aerobic Exercise Training Effects on Omentin-1, Insulin Resistance, and Lipid Profile Among Male Smokers. Res Q Exerc Sport. 2023;94(3):880-5.
https://doi.org/10.1080/02701367.2022.2070116 [DOI:10.1080/02701367.2022.2070116.] [PMID]
33. Kazemi A, Kerendi H, Iranmanesh M. The Effects of Eight Weeks of Aerobic Exercise on Plasma Nesfatin-1, Insulin, Glucose and Insulin Resistance in Obese Women. J Isfahan Med Sch. 2023;41(709):110-7. [DOI:10.48305/jims.v41.i709.0110. [Persian].]
34. Kılıç T, Bağcı C, Göl M, Çelik H, Kaplan DS. Efeitos do exercício físico regular sobre o fluxo sanguíneo da pele e nos fatores de risco cardiovascular em indivíduos com sobrepeso e obesidade. Sci Med. 2022;32(1):e41980.
https://doi.org/10.15448/1980-6108.2022.1.41980 [DOI:10.15448/1980-6108.2022.1.41980.]
35. Asadi V, Azizbeigi K, Khosravi N, Hagh Nazari N. Effect of Exercise Training on Omentin-1 and Vaspin: Comparison of Continuous Endurance, Circuit Resistance, and High Intensity Interval Trainings in Obese Young Men. J Rehab Med. 2019;8(4):103-12. http://dx.doi.org/10.22037/JRM.2019.111421.1980. [Persian]. [DOI:10.5812/jcrps.97880]
36. Sazvar A, Mehrialvar Y, Erfaniadab F. The effect of weight training on the factors involved in fat metabolism in obese and overweight women. EBNESINA. 2020;22(3):30-9. http://ebnesina.ajaums.ac.ir/article-1-890-en.html. [Persian].
37. Hooshmand Moghadam b, Behjat A, Shabkhiz F, Eskandari M, Bakhtiyari A. The effects of Rope Jumping Training and dark chocolate on anthropometric measurements and omentin-1 levels in obese adolescents. J Sabzevar Univ Med Sci. 2021;27(6):710-8. https://jsums.medsab.ac.ir/article_1356.html?lang=en. [Persian].
38. Karajibani M, Montazerifar F, Dehghani K, Mogharnesi M, Mousavi Gilani SR, Dasheipour A. Effect of 10 weeks of speed and endurance exercise and a period of detraining on serum nesfatin-1, lipid profiles , body fat percentage and Body mass index in non-athlete healthy men. Journal of Practical Studies of Biosciences in Sport. 2019;7(14):129-40. [DOI:10.22077/jpsbs.2019.1161. [Persian].]
39. Seyfi Askshahr F, Khajehlandi M. The Effect of 12-Weeks Pilates Body Training on Serum Levels of Apelin and Omentin-1 in Inactive and Overweight Women. J Ardabil Univ Med Sci. 2019;19(3):311-22. http://jarums.arums.ac.ir/article-1-1738-en.html. [Persian]. [DOI:10.29252/jarums.19.3.311]
40. Shafipour Z, Daneshjoo A, Hoseini M. Effect Of Aerobic Training And Walnut Consumption On Nesfatin-1 And Insulin Resistance Index Of Women Type 2 Diabetes. Iran J Endocrinol Metab. 2019; 18(6): 334-41. http://ijdld.tums.ac.ir/article-1-5861-en.html. [Persian].
41. Soori R, Mahmoodi F, Ramezankhani A, Ranjbar K. Effect of 12 weeks resistance training on nesfatn-1 and neuropeptide Y hormones in sedentary obese men. Journal of Practical Studies of Biosciences in Sport. 2019;7(13):99-111. [DOI:10.22077/jpsbs.2019.233.1095. [Persian].]
42. Vaezi p, Zolfaghari MR, Toloueiazar J. Effects of 8 weeks aerobic training on serum level of CTRP9, omentin-1, lipid profile and insulin resistance in inactive obese woman. Journal of Applied Health Studies in Sport Physiology. 2018;5(1):45-52. DOI: 10.22049/JASSP.2019.26537.1209. [Persian].
43. Salimi Avansar M. Effect of HIIT training on the Levels of Omentin-1 and Body composition characteristics in Sedentary Obese Men. Journal of Sport and Exercise Physiology. 2017;10(2):59-68. https://joeppa.sbu.ac.ir/article_98884.html. [Persian].
44. AminiLari Z, Fararouei M, Amanat S, Sinaei E, Dianatinasab S, AminiLari M, et al. The Effect of 12 Weeks Aerobic, Resistance, and Combined Exercises on Omentin-1 Levels and Insulin Resistance among Type 2 Diabetic Middle-Aged Women. Diabetes Metab J.2018;41(3):205-12.
https://doi.org/10.4093/dmj.2017.41.3.205 [DOI:10.4093/dmj.2017.41.3.205.] [PMID] []
45. Ghorbanian B, Nourazarian M, Saberi Y. The effect of one period of progressive resistance training on plasma levels of omentin-1, insulin resistance, non-high density lipoprotein and some cardiovascular risk factors in men.Qom Univ Med Sci J. 2017;11(2):94-103. https://www.sid.ir/paper/688767/en. [Persian].
46. Nasrabadi M, Mogharnasi M. Effect Of Rhythmic Aerobic Exercise On Serum Concentration Of Omentin-1 And Same Anthropometric Markers In Obese Women. Iran J Endocrinol Metab. 2016; 15(3): 192-200. http://ijdld.tums.ac.ir/article-1-5412-en.html. [Persian].
47. Mogharnasi M, Taji Tabas A. The Effect of 10 Weeks of Endurance Training of Cycle Ergometer on Nesfatin-1 Levels and Insulin Resistance in Women with Type 2 Diabetes. Journal of Sport Biosciences. 2016;8(1):95-107. [DOI:10.22059/jsb.2016.58244. [Persian].]
48. Tofighi A, Mehrabani J, Khadivi SM. The effect of 8 weeks aerobic exercise on Nesfatin-1 and acylated Ghrelin in young obese men. Med J Mashad Univ Med Sci. 2014;57(3):562-70. https://mjms.mums.ac.ir/article_3012.html?lang=en. [Persian].
49. Namazizadeh M, Fatolahe Shorabah F, Jalali K, Sheikh Saraf B. The effect of 8 weeks of aerobic exercise on the omentin-1, insulin resistance, CRP, and lipid profile in elderly women with overweight and obesity. Sports medicine and Physical Fitness. 2014; 1: 1-20. https://civilica.com/doc/450303. [Persian].
50. Tavassoli H, Tofighi A, Hossein panah F, Hedaytai M. Appetite and Exercise Influence of 12 Weeks of Circuit Resistance Training on the Nesfatin-1 to Acylated Ghrelin Ratio of Plasma in Overweight Adolescents. Iran J Endocrinol Metab. 2014;15(6):519-26. http://ijem.sbmu.ac.ir/article-1-1587-en.html. [Persian].
51. Saremi A, Asghari M, Ghorbani A. Effects of aerobic training on serum omentin-1 and cardiometabolic risk factors in overweight and obese men. J Sports Sci. 2010;28(9):993-8.
https://doi.org/10.1080/02640414.2010.484070 [DOI:10.1080/02640414.2010.484070.] [PMID]
52. Arab A, Moosavian SP, Hadi A, Karimi E, Nasirian M. The association between serum omentin level and bodyweight: A systematic review and meta-analysis of observational studies. Clinical nutrition ESPEN. 2020;39:22-9.
https://doi.org/10.1016/j.clnesp.2020.06.014 [DOI:10.1016/j.clnesp.2020.06.014.] [PMID]
53. Mogharnasi M, TaheriChadorneshin H, Abbasi-Deloei N. Effect of exercise training type on plasma levels of vaspin, nesfatin-1, and high-sensitivity C-reactive protein in overweight and obese women. Obes Med. 2019; 13: 34-8. http://dx.doi.org/10.1016/j.obmed.2018.12.006. [DOI:10.1016/j.obmed.2018.12.006]
54. Yazici AG. Relationship and interaction between anaerobic sports branches and serum nesfatin-1. Turk J Phys Med Rehab. 2015;61(3):234-40. DOI : 10.5152/tftrd.2015.57124. [DOI:10.5152/tftrd.2015.57124]
55. Nesreen N, Mohsen ES. Moderate exercise training has anorexogenic effect associated with improved oxidative stress in obese women. Int J Nutr Metab. 2015;7(4):52-61. http://dx.doi.org/10.5897/IJNAM2015.0180. [DOI:10.5897/IJNAM2015.0180]
56. Castro Cad, Silva Kad, Rocha MC, Sene-Fiorese M, Nonaka KO, Malavazi I, et al. Exercise and omentin: their role in the crosstalk between muscle and adipose tissues in type 2 diabetes mellitus rat models. Front Physiol. 2019;9:1881.
https://doi.org/10.3389/fphys.2018.01881 [DOI:10.3389/fphys.2018.01881.] [PMID] []
57. Golestani F, Mogharnasi M, Erfani-Far M, Abtahi-Eivari SH. The effects of spirulina under high-intensity interval training on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females: A randomized, controlled, single-blind trial. J Res Med Sci. 2021; 26.
https://doi.org/10.4103/jrms.JRMS_1317_20 [DOI:10.4103/jrms.jrms_1317_20.] [PMID] []
58. Yan P, Liu D, Long M, Ren Y, Pang J, Li R. Changes of serum omentin levels and relationship between omentin and adiponectin concentrations in type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes. 2011:257-63.
https://doi.org/10.1055/s-0030-1269912 [DOI:10.1055/s-0030-1269912.] [PMID]
59. Liu F, Fang S, Liu X, Li J, Wang X, Cui J, et al. Omentin-1 protects against high glucose-induced endothelial dysfunction via the AMPK/PPARδ signaling pathway. Biochem Pharmacol. 2020;174:113830.
https://doi.org/10.1016/j.bcp.2020.113830 [DOI:10.1016/j.bcp.2020.113830.] [PMID]
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