Volume 26, Issue 3 (Autumn 2019)                   J Birjand Univ Med Sci. 2019, 26(3): 279-289 | Back to browse issues page

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Alizadeh L, Sharifzadeh G, Aghajani Y. Epidemiology of head and neck squamous cell carcinoma in birjand city, between 2008 and 2017 . J Birjand Univ Med Sci.. 2019; 26 (3) :279-289
URL: http://journal.bums.ac.ir/article-1-2564-en.html
1- Department of Oral and Maxillofacial Pathology, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran
2- Department of Epidemiology, School of Health, Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
3- Student of Dentistry, Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran , yaaghajani2@yahoo.com
Abstract:   (2553 Views)
Background and Aim:  Squamous cell carcinoma is one of the most common causes of head and neck cancer and is one of the ten leading causes of death in the world and its prognosis is weak due to late diagnosis and varied clinical. Environmental and climatic conditions play a role in cancers; for this reason, the necessity of epidemiological studies is felt. The aim of this study was to evaluate the ten-year epidemiology of cases infected head and neck squamous cell carcinoma in birjand.
Materials and Methods:  This is a cross-sectional descriptive-analytical study, by the method of retrospective study was performed on 111 patients with head and neck squamous cell carcinoma. demographic and histopathological data were extracted from patient records. Subsequently, the data were then analyzed using one-way Chi-square test or Fisherchr('39')s alpha level of α =0.05.
Results: In this study, the mean age of the patients was 60.52 ± 12.9 years and the ratio of male to female was 2.08. The most common sites of involvement were larynx (63.1%) and followed by tongue (8.1%). For smokers, laryngeal involvement was 76.7% and for non-smokers, 54.4%, which is statistically significant (P=0.04). 54.1% of patients had squamous cell carcinoma (SCC) with moderately differentiation. 55% of patients were living in the city. Moderately differentiated tissue lesions among drug users they were significantly higher(P=0.02).
Conclusion:  The results of this study showed that head and neck squamous cell carcinoma has become more prevalent in men, especially the elderly, in recent years. The most common site of involvement in head and neck was the larynx, and smoking significantly increased the prevalence of laryngeal lesions.
Full-Text [PDF 390 kb]   (449 Downloads)    
Type of Study: Original Article | Subject: Pathology
Received: 2018/09/24 | Accepted: 2019/04/30 | ePublished: 2019/09/22

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