Volume 24 - Supplementary                   J Birjand Univ Med Sci. 2017, 24 - Supplementary: 10-21 | Back to browse issues page

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Davoodi M, Peeri M, Azarbayjani M A, Matin Homaee H. A 12- week water aerobic exercise and atorvastatin effect on Changes of Atrial Natriuretic Peptide and Brain Natriuretic Peptide in older men with cardiovascular diseases. J Birjand Univ Med Sci.. 2017; 24 :10-21
URL: http://journal.bums.ac.ir/article-1-2242-en.html
1- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
2- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran. , m.peeri@iauctb.ac.ir
Abstract:   (2166 Views)
Background and Aim: The present study aimed at investigating the effect of a 12-week aerobic water exercise and atorvastatin on of Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) changes in older men with cardiovascular diseases.
Materials and Methods: In the current study, 40 patients with cardiovascular disease, aged 50-65yrs, who were volunteers for the research were divided in to four equal groups including1.exercise, 2.exercise plus atorvastatin, 3.atorvastatin, and 4.control. Then, blood was taken before and after the interventions. Groups 1 and 2 performed the specific water aerobic exercise 3 times a week for 12 weeks. Group 3 took 20mg of atorvastatin daily under a physician Water aerobic exercise lasted 12 weeks, 3 periods a week, with intensity of 55-60% of heart-beat. Every week, due to overtax principle, 3.5 minutes was added to exercise period. In order to determine the difference between pre-test and post-test, dependent T was applied. Intergroup difference was determined through ANOVA using Tukey for post-test; (P≤0.05).
Results: ANOVA application revealed that mean of functional variables in pre-test compared to that of post-test was significantly different. Mean post-test of BNP in the four groups exercise, atorvastatin, exercise plus atorvastatin and control was P= 0.001, P=0.002, P=0.000, respectively. But mean post-test of ANP in the above mentioned groups was P=0.022, P=0.001, P=0.000, respectively.
Conclusion: Aerobic exercises together with daily taking of atorvastatin can have significant effects on decreasing natriuretic peptides and CVDs.
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Type of Study: Original Article | Subject: Physiology
Received: 2017/02/12 | Accepted: 2017/05/9 | Published: 2017/09/27

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