Volume 24 - Supplementary- Biochimistry & Metabolism)
J Birjand Univ Med Sci. 2017, 24 - Supplementary- Biochimistry & Metabolism): 10-21 |
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Davoodi M, Peeri M, Azarbayjani M A, Matin Homaee H. A 12- week water aerobic exercise and atorvastatin effect on Changes of Atrial Natriuretic Peptide and Brain Natriuretic Peptide in older men with cardiovascular diseases. Journals of Birjand University of Medical Sciences 2017; 24 :10-21
URL: http://journal.bums.ac.ir/article-1-2242-en.html
URL: http://journal.bums.ac.ir/article-1-2242-en.html
1- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
2- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran. ,m.peeri@iauctb.ac.ir
2- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran. ,
Abstract: (11959 Views)
Background and Aim: The present study aimed at investigating the effect of a 12-week aerobic water exercise and atorvastatin on of Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) changes in older men with cardiovascular diseases.
Materials and Methods: In the current study, 40 patients with cardiovascular disease, aged 50-65yrs, who were volunteers for the research were divided in to four equal groups including1.exercise, 2.exercise plus atorvastatin, 3.atorvastatin, and 4.control. Then, blood was taken before and after the interventions. Groups 1 and 2 performed the specific water aerobic exercise 3 times a week for 12 weeks. Group 3 took 20mg of atorvastatin daily under a physician Water aerobic exercise lasted 12 weeks, 3 periods a week, with intensity of 55-60% of heart-beat. Every week, due to overtax principle, 3.5 minutes was added to exercise period. In order to determine the difference between pre-test and post-test, dependent T was applied. Intergroup difference was determined through ANOVA using Tukey for post-test; (P≤0.05).
Results: ANOVA application revealed that mean of functional variables in pre-test compared to that of post-test was significantly different. Mean post-test of BNP in the four groups exercise, atorvastatin, exercise plus atorvastatin and control was P= 0.001, P=0.002, P=0.000, respectively. But mean post-test of ANP in the above mentioned groups was P=0.022, P=0.001, P=0.000, respectively.
Conclusion: Aerobic exercises together with daily taking of atorvastatin can have significant effects on decreasing natriuretic peptides and CVDs.
Materials and Methods: In the current study, 40 patients with cardiovascular disease, aged 50-65yrs, who were volunteers for the research were divided in to four equal groups including1.exercise, 2.exercise plus atorvastatin, 3.atorvastatin, and 4.control. Then, blood was taken before and after the interventions. Groups 1 and 2 performed the specific water aerobic exercise 3 times a week for 12 weeks. Group 3 took 20mg of atorvastatin daily under a physician Water aerobic exercise lasted 12 weeks, 3 periods a week, with intensity of 55-60% of heart-beat. Every week, due to overtax principle, 3.5 minutes was added to exercise period. In order to determine the difference between pre-test and post-test, dependent T was applied. Intergroup difference was determined through ANOVA using Tukey for post-test; (P≤0.05).
Results: ANOVA application revealed that mean of functional variables in pre-test compared to that of post-test was significantly different. Mean post-test of BNP in the four groups exercise, atorvastatin, exercise plus atorvastatin and control was P= 0.001, P=0.002, P=0.000, respectively. But mean post-test of ANP in the above mentioned groups was P=0.022, P=0.001, P=0.000, respectively.
Conclusion: Aerobic exercises together with daily taking of atorvastatin can have significant effects on decreasing natriuretic peptides and CVDs.
Type of Study: Original Article |
Subject:
Physiology
Received: 2017/02/12 | Accepted: 2017/05/9 | ePublished: 2017/09/27
Received: 2017/02/12 | Accepted: 2017/05/9 | ePublished: 2017/09/27
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