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Background and Aim: Nonalcoholic fatty liver disease is the most common cause of abnormal liver enzymes. We aimed to investigate the effects of of resistance and combined exercise on levels of liver enzymes in women with fatty liver disease Materials and Methods: In this study, 37 women were assigned into three groups including control, resistance and combined exercise groups. Resistance exercise protocol included 8 movements, 3 sets, 8-10 repetitions which performed at %60-75 of one repetition maximum، 3 times per week for 8 weeks. Combined exercise included 4 resistance movement in the first half of training session and the aerobic exercise at intensity of %60-75 maximum heart rate in the other half. The AST, ALT and ALP were measured using biochemical methods. Paired t-test results for the extraction of one-way ANOVA , at a significant level of 0/05 were analysed. Results: The level of ALP only in the resistance exercise group significantly decreased (p=0.03), but AST and ALT levels did not significantly change in any groups (p>0.05). The mean of ALT/AST ratio significantly increased in the resistance exercise group (p =0.04), but no significant changes were observed in the combination and control groups. The mean of flexibility (p=0.001), maximal oxygen consumption (p=0.02), muscle strength (p=0.003) and grip strength (p=0.001), significantly increased after resistance exercise. Conclusion: None of the resistance and combined exercises had significant effect on the levels of AST and ALT, but the resistance exercise improved ALP and fitness indicators.Therefore, resistance exercise may be more favorite for fatty liver patients.