Search published articles


Showing 2 results for Lactate Dehydrogenase

Asma Soleimani, Seed Shakerian, Ruhollah Ruhollah,
Volume 24, Issue 3 (11-2017)
Abstract

Background and Aim: Since the intensity and duration of exercise and recovery time are one of the influencing factors on injuries and adaptations, the current study examined changes in muscle damage active in overweight male students after exhaustive aerobic and anaerobic exercises.
Materials and Methods: In this semi-experimental study, 22 overweight male students were randomly divided into experimental (n = 12) and control (n = 10) groups.The subjects first tested the aerobic test of astrand (including running on a treadmill at the rates of 5 to 8 mph with a gradient of 0, for 3 minutes, and after 3 minutes every 2 minutes, a steep gradient of 2.5%, and the rate was constant and the activity continued until the time of exhaustion, and one week after an anaerobic Rast test (including 6 repetitions of two fast running 35 meters and with a maximum intensity performed after the rest interval of 10 seconds in each repetition) The control group continued to their daily activities without any interruption. Finally, the obtained data were analyzed through covariance and T-dependent analyses at the significant level of 0.05.
Results: It was found that in the pre-test, post-test LDH(17.16±0.9), AST(140±5.61) and CPK(147.5±7.65) levels in the experimental group, compared to the control, due to aerobic and anaerobic exercise, showed a significant increase. The level of CPK and LDH between the experimental and control groups was significant in aerobic exercise (P≤ 0.05), (P≤ 0.01); respectively, and in anaerobic exercise (P = 0.004), (P = 0.006) ; respectively, but the AST values between the two groups increased except for the aerobic exercise sessions (P = 0.7), (P = 0.1); respectively.
Conclusion: In general, the study showed that the muscle damage in exhausted aerobic exercise is less than that in anaerobic exercise. Thus, it is recommended that performing aerobic and anaerobic activities should be done at appropriate resting intervals.
 


Fatemeh Kazeminasab, Sara Soltani, Elham Alahyari, Nasim Behzadnejad, Mohammad Javad Pourvaghar,
Volume 31, Issue 4 (12-2024)
Abstract

Background and Aims: Branched-chain amino acid (BCAA) supplementation is used as a nutritional strategy to reduce muscle soreness in athletes. The present study aimed to investigate the effect of BCAA supplementation on muscle soreness and muscle damage factors after exercise in healthy adults.
Materials and Methods: A systematic search of articles published in English and Persian databases until November 2023 (without limiting the year of publication) was conducted to the effect of BCAA supplementation on muscle soreness and markers of muscle damage, including creatine kinase (CK), lactate dehydrogenase (LDH) and myoglobin (MB) was investigated in healthy adults.
Results: A total of 28 studies, including 528 subjects, were included in the present meta-analysis. The results showed that BCAA supplementation significantly reduced muscle soreness at 24, 48, and 72 h after exercise compared with the control group (P<0.05); however, it was not significant immediately after exercise. This supplementation caused a significant decrease in CK and LDH immediately, 48 hours after exercise, compared with the control group (P<0.05). In addition, BCAA supplementation caused a significant decrease in circulating myoglobin after exercise in athletes and non-athletes compared with the control group (P<0.05).
Conclusion: Using BCAA supplementation can be considered a useful and effective strategy for athletes to reduce muscle soreness (24-72 hours after exercise) and muscle damage markers, including CK (48-72 hours after exercise) and LDH (48 hours after exercise).


Page 1 from 1     

© 2025 CC BY-NC 4.0 | Journal of Translational Medical Research

Designed & Developed by : Yektaweb