Sh. Jafari Giv, E. Abdorrahim Kashi, H. Ghani, Gha. Moosavi, M. Afshar,
Volume 12, Issue 3 (October & January 2005)
Abstract
Background and Aim: Different methods for appendectomy operation wound repairs have been applied. The two common methods of the wound repair in suppurative phase of appendicitis are subcuticular and interrupted wound repair. There have been controversies on the benefit of each method. This Study was designed to compare the two methods of appendectomy wound repair on wound infection after suppurative appendectomy
Materials and Methods: Two hundred patients who had necessary conditions for participating in survey were divided randomly into 2 groups in 2003. In the first group, operational wounds were repaired by subcuticular method and in the second by interrupted transdermal technique. Then the patients in the two groups were visited by another surgeon unaware of the type of suturation at intervals of one week and one month after operation. The results on the rate and kind of wound infection, pus secretion, wound opening and systemic infections were compared by SPSS software using Chi-Square and fisher exact tests. P<0.05 was considered as the significant level.
Results: The mean age of patients in interrupted transdermal and subcuticular groups were 20.85±6.7 and 20.61±6.58 yrs (P=0.8), respectively. Sexes of the two groups were also similar with male dominating of 54% and 53% in transdermal and subcuticular groups, respectively (P=0.89). Local infection rates in subcuticular and transdermal group one week after surgeries were 9% and 6%, respectively (P=0.421). Rates of pus secretion and wound opening one week after surgery in subcuticular and transdermal group, were 5% and 4% respectively (P=0.99). No Systemic infection was found one week and one month after operation in both groups.
Conclusion: Sine there were no statistical significant differences between the two methods of subcuticular and interrupted transdermal wound repair in supportive appendectomy either of them could be used.
Borhan Mansouri, Maryam Rezaei, Seyed Yoosef Javadmoosavi, Alireza Amirabadi,
Volume 27, Issue 1 (Spring 2020)
Abstract
Background and Aim: Metabolic thyroid disease is one of the most common diseases in adults. On the other hand, environmental pollutants, including heavy metals, can interfere with hormonal function. So, the aim of this study was to evaluate the serum level of magnesium, manganese, and selenium in patients with hypothyroidism, hyperthyroidism and thyroid cancer in South Khorasan in 2018.
Materials and Methods: In this study, 77 patients were evaluated in three groups: hypothyroidism (n=33), hyperthyroidism (n=33) and cancer (n=11). After receiving the consent of the patients, their demographic information were collected. Sampling was convenient sampling method. Then, 10 ml of venous blood after 12 hours of fasting were taken. After the serum preparation, the levels of trace elements were assayed by ICP-MS.
Results: The mean level of the studied metals (except for manganese) were not significantly different in the three groups (p> 0.05). The level of magnesium, manganese, and selenium in the hypothyroidismwere 1.74±0.55, 6.30±4.88, and 1.38±0.80; in the hyperthyroidism were 1.77±0.41, 5.55±4.55, and 1.47±0.70; and in the thyroid cancer group were 2.07±0.81, 6.02±2.22 and 1.84±1.03 respectively (p<0.05).
Conclusion: According to the findings of this study, the changes in the trace element status can lead to a type of thyroid disorder, or even these disorders may alter the serum levels of these metals. But this difference, except for manganese metal, was not significant in other cases, however, further studies with other metals and elsewhere are recommended.
Elaheh Moosavi, Samaneh Enayati, Sepideh Borhan, Maryam Mehrpooya, Mahsa Mohammad Amoli,
Volume 27, Issue 4 (Winter 2020)
Abstract
In-stent restenosis (ISR) is regarded as the main problem in the utilization of stents in the treatment of coronary artery atherosclerotic stenosis in percutaneous coronary intervention (PCI). This study investigated the possible role of the G22A variant of the Adenosine Deaminase gene (ADA) in the development of ISR. In this study, 91 patients who underwent PCI were divided into two groups of case with ISR (n=40) and control without ISR after six months from stenting (n=51). The case and control groups were matched in terms of age and gender. The genotypes of the G22A variant in the samples were examined by the molecular method of PCR-RFLP and electrophoresis. The results were statistically analyzed using t-test, and the results showed that the frequency of allele A of variant G22A in the (+ISR) group was higher than that in the (-ISR) group. However, there was no significant relationship between the distribution of allele and genotype frequency of this variant with the incidence of ISR (P>0.05).