Showing 5 results for Izadi
P. Mohajeri, B. Izadi, M. Rezaie, B. Falahi,
Volume 18, Issue 1 (April 2011)
Abstract
Background and Aim: Due to the role of spreading infections in hospitals, drug resistant Staphylococcus aureus nasal carriers have always been considered. Clindamycin is one of the effective drugs against the bacteria, but some isolates have acquired induced resistance. This study was preformed to investigate the prevalence and characteristics of resistant isolates in nasal carriers of hospital origin, in Imam Reza Hospital, as the largest hospital in Kermanshah province.
Materials and Methods: This cross-sectional study was performed on the patients which their nasal samples were positive for Staphylococcus aureus after hospitalization, in the year 2009. Sensitivity of the isolates to erythromycin and clindamycin was determined. Induced, constitutive resistance and MS phenotype were evaluated by D-test. Data were analyzed by means of SPSS version 16 and chi-square test at the significant level of P<0.05.
Results: Among 1269 admitted patients, 210 (16.5%) were hospital acquired-nasal carriers for the bacteria. The frequency of resistant isolates to erythromycin and clindamycin was 41.5% and 23.3%, respectively. The induced, constitutive and MS phenotype were 10%, 23.3% and 8.6% of isolates, respectively. A significant difference between MRSA (19.5%) and MSSA (3.9%) isolates with induced resistance was seen (P=0.001).
Conclusion: Carrier patients of the resistant variants of Staphylococcus aureus are always a serious threat to their own health and others. Regarding the frequency of induced resistance to clindamycin, screening Staphylococcus aureus isolates in this regard, seems to be essential.
M Eizadi, Gh Baghery, H Masroor, L Behboodi, H Dooaly,
Volume 18, Issue 4 (January 2011)
Abstract
Background and Aim: Ghrelin, a 28-amino acid peptide, plays an important role in weight regulation and energy homeostasis. In this study, Ghrelin responses to a long-term aerobic exercise in obese men was studied. Materials and Methods: In this semi-experimental study, thirty adult obese males were randomly divided into a physically active (experimental) or a physically inactive (control) groups. Serum Ghrelin, lipid profile (TG, TC, LDL, HDL) and anthropometrical indexes were measured respectively before and after a 12 week aerobic exercise and detraining in the experimental and control groups. Blood samples were taken from all participants after an overnight fasting (12 hours). Statistical analysis was performed by means of SPSS software (version 15) using T-test method. Results: Aerobic exercise led to a significant decrease in serum Ghrelin and all anthropometrical indexes in the experimental group (P<0.05). In addition, TG concentration and ratio of TG to HDL decreased after aerobic exercise in the experimental group (P<0.05). All variables remained constant in the control group after detraining. Conclusion: The findings of the present study show that an exercise program, while significantly decreasing serum Ghrelin level, can be followed by weight loss and a decrease in fat tissues in obese men.
Mojtaba Eizadi, Yaser Kazemzade, Laleh Behbudi, Abdolali Banaeifar,
Volume 20, Issue 4 (January 2013)
Abstract
Background and Aim: Obesity is associated with some chronic morbidity including atherosclerosis, hypertension, and type 2 diabetes which are major components of metabolic syndrome. In the present study, association between insulin resistance and adiponectin, as an anti-inflammatory cytokine, in type 2 obese male diabetics was assessed. Materials and Methods: In this descriptive study, fasting serum adiponectin, insulin, glucose and insulin resistance were measured in 42 obese male type 2 diabetics (aged 37 - 53 years, weight 80-100kg, 30≤BMI≤36). Pearson’s correlation method was used to determine the association between adiponectin levels with insulin resistance, glucose, and insulin in the cases (P≤0.05). Results: Pearson’s correlation method showed a significant negative association between serum adiponectin andinsulin resistance (P=0.000(. Besides, a significant correlation was observed between adiponectin level and fasting glucose (P=0.005). But, no correlation was found between serum adiponectin and insulin (P=0.196). Conclusion: The current study demonstrated that serum adiponectin level, as an anti-inflammation and anti-diabetic cytokine, is a predictive factor of insulin resistance in type 2 diabetics.
Mojtaba Eizadi, Yahya Sokhanguei, Anoosh Eghdami, Abdolali Banaeifar,
Volume 21, Issue 2 (July 2014)
Abstract
Background and Aim: Exercise helps in the favorable function of insulin.The obese people have metabolic complications. Thus, the present study aimed at investigating the effect of aerobic exercises on pancreas Beta- cells function in obese men. Materials and Methods: In this semi-experimental study, fasting levels of glucose, insulin, triglyceride, and pancreas beta cells function in two equal randomized groups of obese men i.e. the experimental group (28 men) and the control group ( 14 normal weight men men) were compared with those of a group ofThe experimental group participated in a three month aerobic training and the control group were banned from any exercise training during this period. Anthropometrical and biochemical indices in the experimental and control groups were measured again after the period of three months . Independent T test was used for comparison between the two groups Paired ‘t’ test was applied to compare the pre- and post-training values. Results: It was found that obese subjects have a lower beta cells function and higher glucose and triglyceride levels compared to normal weight men (p ≤ 0.05). Beta-cells function significantly increased after aerobic exercise in the experimental group (p = 0.019). In addition, fasting glucose (p = 0.023) and triglyceride (p = 0.031) concentrations and anthropometrical indexes such as body weight (p = 0.028), body fat percentage (p = 0.016) , and body mass index (p = 0.024) decreased due to exercise intervention in the experimental group. A significant negative relationship between beta cells function and FBS was diagnosed after the exercise program (P=0.014, r=0.68). Conclusion: Aerobic exercise training increases beta cells function and decreases FBS in obese men. These findings support the hypothesis that regular physical activity postpones the occurrence of type 2 diabetes in adult obese subjects.
Hanieh Salmani Izadi, Solmaz Hasani,
Volume 31, Issue 3 (November 2024)
Abstract
Sheehan syndrome, also known as postpartum hypopituitarism, is a very serious complication of postpartum hemorrhage. It usually remains underdiagnosed years after delivery as symptoms may be subtle, especially in developing countries due to poor obstetric care and home deliveries. This case report highlights the importance of recognizing atypical presentations, such as hypoglycemic attacks, to help with early diagnosis and better management.
A female 34-year-old, G4P2Ab2L2, presented with a low level of consciousness, diaphoresis, and severe hypoglycemia after C-section delivery. Adetailed history revealed a history of failure of lactation following her first vaginal delivery, 8 years ago, accompanied by no complication or history of postpartum hemorrhage. She has experienced a few episodes of hypotension, malaise, and hypoglycemia afterward. Laboratory examination displayed adenohypophyseal insufficiency as evident from low blood glucose level in the presence of low levels of cortisol, Adrenocorticotropic hormone (ACTH), and prolactin. Sheehan syndrome was confirmed with Magnetic resonance imaging (MRI) of the pituitary as an empty sella turcica consistent with the provisional diagnosis. This case report emphasizes the significance of early suspicion in cases presented with less known complications of Sheehan's syndrome as recurrent symptomatic episodes of hypoglycemia and management of this easily missed and treatable condition.
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