Journal of Translational Medical Research

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  Background and Aim: Urinary tract infection is one of the most prevalent bacterial infections in childhood, which due to an inapproto determine the common bacteria and their antibiotic susceptibility in children with urinary tract infection.

  Materials and Methods: This descriptive-analytical and prospective study was done in 2009-2010 on urine samples of all children under 13 years who had been referred to Emmam-Reza hospital laboratory in Birjand and had positive urine culture. Sex and age of children, the kind of isolated bacteria in urine culture, susceptibility and resistance of these bacteria to current antibiotics were studied.The obtained data was analyzed by means of SPSS using Fisher exact- test.

  Results: 100 children (84 girls and 16 boys) with positive urine culture were studied. The most common age of urinary tract infection was under two years. In all ages the rate of urinary tract infection in females was more than males. E.coli was the most common cause in both sexes. There was a significant relationship between kind of microorganism and age of infection. The most prevalent cause of urinary tract infection in all ages was E.coli (75%) ,infection by Proteus was 11%, and other microorganism caused 14% of the cases. E.coli had the most susceptibility to ceftriaxone and ceftazidime and the most resistance to cephalexin and co-trimoxazol. Not taking the type of microorganism into consideration, the most sensitive antibiotics were ceftazidime, ceftriaxone, cefexim and nalidixic acid and the most resistance was against co-trimoxasol and cefalexin.

  Conclusion: Regarding the results, it is recommended to use cefexime and nalidixic acid for outpatient treatment of urinary infection , and ceftazidime and ceftriaxon for inpatient treatment.Selecting of antibiotics for urinary infection therapy should be based on the local prevalence of pathogenic bacteria and antibiotic sensitivities rather than on a universal guideline.

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Background and Aim: Maintaining a huge elderly health, health promotion and community development is very important. Workers' health status is largely influenced by their working conditions and job. Work in mines, including those considered threats to workers' health.

Materials and Methods: A number of 45 workers in each of the control and intervention groups participated in a quasi-experimental study. Demographic information and data related to HAM constructs and safety were collected through a HAM questionnaire and the safe operation checklist 3 months after the intervention. Cronbach's alpha coefficients were used to confirm properties of the tools. Educational intervention accompanied was applied in the form of four training classes. The Data were analyzed based on distribution of variables.

Results: Before the intervention, there was no significant difference between the two groups in terms of demographics and the study main variables. After training, however, results showed significant changes of mean scores of attitude (P<0.001), norms (P<0.001), belief (P<0.001), intention (P<0.001), knowledge (P<0.001) in the experimental group.

Conclusion: The research results show that HAM educational intervention is able to change workers’ awareness, attitude, norm, belief, and intention towards unsafe behavior and improve their safety performance.

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Extract of Anacyclus Pyrethrum contains materials which the potential to affect the tissues of the testis. The aim of the present study was to identify the histological effects of aqueous extract of AP on Rat testis. In this experimental study 48 adult male Wister rats were chosen and divided into experimental (36 rats) and control (12 rats) groups. The rats in the experimental group were divided into three subgroups, one, two and three, and each subgroup received 50, 100 and 150 mg/kg doses of the extract intraperitoneally for four weeks, respectively. The rats were then placed under deep anesthesia and samples were collected from their testicles and paraffin blocks were prepared. Histological sections with 6 µm thickness were prepared and stained with H&E method and variables (internal and external and thickness of germinal epithelium) were measured in at least in 100 somniferous tubules in each rat. Statistical analysis showed that there was a significant difference between control and experimental groups and for external and internal diameters (p<0.002). Although there was no any significant difference for an epithelial thickness between control and experimental 50 mg/kg, there was a significant difference between control and other experimental groups (p<0.002). It seems that aqueous extract of Anacyclus pyrethrum could change epithelial thickness, internal and external diameters of seminiferous tubule Rat testis.