Volume 31, Issue 4 (February 2024)                   J Birjand Univ Med Sci. 2024, 31(4): 302-310 | Back to browse issues page

Research code: 456843
Ethics code: IR.BUMS.REC.1401.271


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Farazi M, Hazari V, Salehinia H. Investigation of different etiologies of infertility in patients referred to Birjand infertility center, 2021-2022. J Birjand Univ Med Sci. 2024; 31 (4) :302-310
URL: http://journal.bums.ac.ir/article-1-3451-en.html
1- Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
2- Department of Gynecology, School of Medicine, Valiasr Hospital, Birjand University of Medical Sciences, Birjand, Iran , dr.vhazari@gmail.com
3- Department of Epidemiology and Biostatistics, School of Health Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran
Abstract:   (655 Views)
Background and Aims: A significant part of infertility has been related to environmental conditions as well as acquired risk factors. Different environmental conditions emphasize the necessity of studying different etiologies of infertility in each region. The present study aimed to determine the etiologies of infertility in infertile couples.
Materials and Methods: In this cross-sectional study, 583 infertile men and women referred to the infertility clinic from 2021 to 2022 were examined. In addition, sampling was performed using the census method. Information about patients was obtained from medical tests and laboratory findings. It is noteworthy that descriptive statistics, such as frequency and mean, were used to analyze the data.
Results: According to the results, oligospermia was the most common cause of male infertility (44.72%), and ovulation disorder was the most prevalent reason for female infertility (66.17%). In general, ovulation disorder and sperm motility were the most common causes of infertility (36.73%). There was no significant relationship between women's underlying diseases and the causes of infertility (P>0.05).
Conclusion: The etiology pattern of infertility is closely similar to that of many other regions reported by the World Health Organization (WHO). Despite this, the rate of ovarian disorders is higher than that in many other studies, which needs further studies.
Full-Text [PDF 385 kb]   (255 Downloads)    
Type of Study: Original Article | Subject: Gynecology & Obstetrics
Received: 2024/08/7 | Accepted: 2024/12/31 | ePublished ahead of print: 2025/02/3 | ePublished: 2024/12/25

References
1. Shen D, Yang S, Qi C, Yang H. Global, Regional, and National Prevalence and Disability-Adjusted Life-Years for Female Infertility: Results from a Global Burden of Disease Study, 1990-2019. Gynecol Obstet Invest. 2024: 1-17. DOI: 10.1159/000542408 [DOI:10.1159/000542408]
2. Sharma A, Shrivastava D. Psychological problems related to infertility. Cureus. 2022; 14(10): e30320. DOI: 10.7759/cureus.303203. [DOI:10.7759/cureus.30320]
3. Carson SA, Kallen AN. Diagnosis and management of infertility: a review. Jama. 2021; 326(1): 65-76. DOI: 10.1001/jama.2021.4788 [DOI:10.1001/jama.2021.4788] [PMID] []
4. Cox CM, Thoma ME, Tchangalova N, Mburu G, Bornstein MJ, Johnson CL, et al. Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis.Hum Reprod Open. 2022; 2022(4): hoac051. DOI: 10.1093/hropen/hoac051 [DOI:10.1093/hropen/hoac051] [PMID] []
5. Imannezhad Sh, Mirzaei M, Khodadadi B, Heydari O, Dehghani N. Prevalence of Infertility among Iranian Women: An Overview of Systematic Reviews and Meta-Analyses. Health Provid 2024; 4(1): 1-8. DOI: 10.22034/HP.2024.451486.1043
6. Moghadam AD, Delpisheh A, Sayehmiri KJNPT. The trend of infertility in Iran, an original review and meta-analysis. 2014; 1(1): 46-52. URL: https://npt.tums.ac.ir/index.php/npt/article/view/8
7. Abangah GH, Rashidian T, Parizad Nasirkandy M, Azami M. A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran. Int J Fertil Steril. 2023; 17(3): 160-73. URL: 10.22074/ijfs.2023.541991.1215
8. Akhondi MM, Ranjbar F, Shirzad M, Behjati Ardakani Z, Kamali K, Mohammad K. Practical Difficulties in Estimating The Prevalence of Primary Infertility in Iran. Int J Fertil Steril. 2019; 13(2): 113-7. DOI: 10.22074/ijfs.2019.5583
9. Saei Ghare Naz M, Ozgoli G, Sayehmiri K. Prevalence of Infertility In Iran: A Systematic Review And Meta-Analysis. Urol J. 2020; 17(4): 338-45. DOI: 10.22037/uj.v0i0.5610
10. Madani T, Zaferani F, Peyrovan S, Eshrati B. Identification of influential factors on ovarian responsiveness with tamoxifen in type-2 WHO anovulatory patients. J Mazandaran Univ Med Sci. 2005; 15(48): 65-72. URL: http://jmums.mazums.ac.ir/article-1-10-en.html
11. Shirani M, Zareie A, Meraci M, Askari G. The Association between Physical Activity and Sperm Quality Parameters: A Cross-Sectional Study in Iranian Infertile Men. J Health Syst Res. 2021; 17(2): 80-6. URL: http://hsr.mui.ac.ir/article-1-1293-en.html
12. Macaluso M, Wright-Schnapp TJ, Chandra A, Johnson R, Satterwhite CL, Pulver A, et al. A public health focus on infertility prevention, detection, and management. Fertil Steril. 2010; 93(1): 16. e1-. e0. DOI: 10.1016/j.fertnstert.2008.09.046 [DOI:10.1016/j.fertnstert.2008.09.046] [PMID]
13. Aflatounian A, Seyed HS, Tabibnezhad N. The epidemiological and etiological aspects of infertility in Yazd province of Iran. Iran J Reprod Med. 2009; 7(3): 117-22. Corpus ID: 223800213.
14. 14 Safarinejad MR. Infertility among couples in a population‐based study in Iran: prevalence and associated risk factors. Int J Androl. 2008; 31(3): 303-14. DOI: 10.1111/j.1365-2605.2007.00764.x [DOI:10.1111/j.1365-2605.2007.00764.x] [PMID]
15. Masoumi SZ, Parsa P, Darvish N, Mokhtari S, Yavangi M, Roshanaei G. An epidemiologic survey on the causes of infertility in patients referred to infertility center in Fatemieh Hospital in Hamadan. Iran J Reprod Med. 2015; 13(8): 513-6. PMCID: PMC4637117
16. Luciano AA, Lanzone A, Goverde AJ. Management of female infertility from hormonal causes. Int J Gynaecol Obstet. 2013; 123: S9-S17. DOI: 10.1016/j.ijgo.2013.09.007 [DOI:10.1016/j.ijgo.2013.09.007] [PMID]
17. Karimpour AA, Esmaeelnezhad Moghadam A, Moslemizadeh N, Mousanezhad N, Peyvandi S, Gahandar M. Incidence and main causes of infertility in patients attending the infertility center of Imam khomeini hospital in 2002-2004. J Mazandaran Univ Med Sci. 2005; 15(49): 44-9. URL: http://jmums.mazums.ac.ir/article-1-790-en.html.
18. Esmaeilzadeh S, Farsi M, Nazari T. The cause of infertility frequency in the patients referring to Babol township fatemeh zahra infertility center from May 1996 to May 1998. J Mazandaran Univ Med Sci. 2002; 12(35): 29-34. URL: http://jmums.mazums.ac.ir/article-1-82-en.html
19. Das S, Nardo LG, Seif MW. Proximal tubal disease: the place for tubal cannulation. Reprod Biomed Online. 2007;15(4): 383-8. DOI: 10.1016/s1472-6483(10)60362-8 [DOI:10.1016/S1472-6483(10)60362-8] [PMID]
20. Berek, J.S. Berek & Novak's Gynecology: 14th Edition, Lippincott Williams and Wilkins, Philadelphia, 2007.
21. Malekshah AK, Moghaddam AE, Moslemizadeh N, Peivandi S, Barzegarnejad A, Musanejad N, et al. Infertility in Mazandaran province-north of Iran: an etiological study. Iran J Reprod Med. 2011; 9(1): 21-4. PMCID: PMC4212141
22. Ghahramani F, Ghaem H. The effective factors on men infertility: a case-control study. J Gorgan Univ Med Sci. 2005; 7(2): 42-5. URL: http://goums.ac.ir/journal/article-1-34-en.html
23. Smit M, Romijn JC, Wildhagen MF, Veldhoven JL, Weber RF, Dohle GR. Decreased sperm DNA fragmentation after surgical varicocelectomy is associated with increased pregnancy rate. J Urol. 2010; 183(1): 270-4. DOI: 10.1016/j.juro.2009.08.161 [DOI:10.1016/j.juro.2009.08.161] [PMID]
24. Gupta C, Chinchole A, Shah R, Pathak H, Talreja D, Kayal A. Microscopic varicocelectomy as a treatment option for patients with severe oligospermia. Investig Clin Urol. 2018; 59(3): 182-6. DOI: 10.4111/icu.2018.59.3.182 [DOI:10.4111/icu.2018.59.3.182] [PMID] []
25. Majzoub A, ElBardisi H, Covarrubias S, Mak N, Agarwal A, Henkel R, et al. Effect of microsurgical varicocelectomy on fertility outcome and treatment plans of patients with severe oligozoospermia: an original report and meta‐analysis. Andrologia. 2021; 53(6): e14059. DOI: 10.1111/and.14059 [DOI:10.1111/and.14059] []
26. Liang S, Chen Y, Wang Q, Chen H, Cui C, Xu X, et al. Prevalence and associated factors of infertility among 20-49 year old women in Henan Province, China. Reprod Health. 2021; 18(1): 254. DOI: 10.1186/s12978-021-01298-2 [DOI:10.1186/s12978-021-01298-2] [PMID] []
27. Nik Hazlina NH, Norhayati MN, Shaiful Bahari I, Nik Muhammad Arif NA. Worldwide prevalence, risk factors and psychological impact of infertility among women: a systematic review and meta-analysis. BMJ open. 2022; 12(3): e057132. DOI: 10.1136/bmjopen-2021-057132 [DOI:10.1136/bmjopen-2021-057132] [PMID] []

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