Volume 21, Number 4 (January 2015)                   J Birjand Univ Med Sci. 2015, 21(4): 416-424 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Khazraei H, khodami N, Amani S, Shahtoosi M, Khodami A. The Comparison of Ginkgo biloba and Cinnarizine effectiveness in tinnitus intensity of patients with subjective tinnitus. J Birjand Univ Med Sci.. 2015; 21 (4) :416-424
URL: http://journal.bums.ac.ir/article-1-1570-en.html

1- Assistant professor, Department of ENT, Shahrekord University of Medical Sciences, Shahrekord, Iran; , na.khodami@ymail.com
2- General Practitioner, Esfahan University of Medical Sciences, Esfahan, Iran.
3- Assistant professor, Department of ENT, Shahrekord University of Medical Sciences, Shahrekord, Iran
4- Assistant professor, Department of Dentistry, Arak University of Medical Sciences, Arak, Iran
5- Department of ENT, Esfahan University of Medical Sciences, Esfahan, Iran
Abstract:   (6250 Views)
Background and Aim: Subjective Tinnitus is one of the common problems in the world whose prevalence is estimated to be 7-20 percent in the community. In the present study, effectiveness of Ginkgo biloba with that of cinnarizine on subjective tinnitus were compared and assessed in order to determine the effective dose of Ginko on .patients. Materials and Methods: This clinical trial study conducted on 61 patients with subjective tinnitus who had been referred or had come to Shahrekord ENT clinic .The patients who did not have certain pathologic physical problems .were randomly divided into two groups (Cinnarizine & Ginko biloba).The patients filled out .Tinnitus Severity Index (TSI) form and after 2 months they were assessed. The obtained data was analyzed by means of SPSS software (V: 17) using chi-square, paired t test, and independent T test. Results: According to the findings in Ginkgo Biloba group the two criteria the severity of tinnitus and the .adverse changes in quality of life significantly reduced after treatment (P=0.001, P=0.006), respectively. In Cinnarizine group, both criterion reduced after treatment, but just the severity of tinnitus decreased significantly (P=0.006). The overall response to treatment in Ginkgo Biloba group was significantly higher than Cinnarizine group, but the difference was not significant (P>0.05). Conclusion: It was found that after two months of treatment with Ginkgo biloba (120-140 mg daily) tinnitus severity and the adverse changes on quality of life significantly decreased in the patients, whereas Cinnarizine did not reduce the latter significantly. However, no significant difference was observed between the two groups (Cinnarizine & Ginko biloba).
Full-Text [PDF 277 kb]   (1367 Downloads)    
Type of Study: Original Article | Subject: ENT
Received: 2014/02/1 | Accepted: 2014/11/26 | Published: 2015/02/4

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Journal of Birjand University of Medical Sciences

Designed & Developed by : Yektaweb