Journals of

Background and Aim: Exercise helps in the favorable function of insulin.The obese people have metabolic complications. Thus, the present study aimed at investigating the effect of aerobic exercises on pancreas Beta- cells function in obese men. Materials and Methods: In this semi-experimental study, fasting levels of glucose, insulin, triglyceride, and pancreas beta cells function in two equal randomized groups of obese men i.e. the experimental group (28 men) and the control group ( 14 normal weight men men) were compared with those of a group ofThe experimental group participated in a three month aerobic training and the control group were banned from any exercise training during this period. Anthropometrical and biochemical indices in the experimental and control groups were measured again after the period of three months . Independent T test was used for comparison between the two groups Paired ‘t’ test was applied to compare the pre- and post-training values. Results: It was found that obese subjects have a lower beta cells function and higher glucose and triglyceride levels compared to normal weight men (p ≤ 0.05). Beta-cells function significantly increased after aerobic exercise in the experimental group (p = 0.019). In addition, fasting glucose (p = 0.023) and triglyceride (p = 0.031) concentrations and anthropometrical indexes such as body weight (p = 0.028), body fat percentage (p = 0.016) , and body mass index (p = 0.024) decreased due to exercise intervention in the experimental group. A significant negative relationship between beta cells function and FBS was diagnosed after the exercise program (P=0.014, r=0.68). Conclusion: Aerobic exercise training increases beta cells function and decreases FBS in obese men. These findings support the hypothesis that regular physical activity postpones the occurrence of type 2 diabetes in adult obese subjects.