The effect of dexamethasone on reducing postoperative nausea and vomiting following tonsillectomy

JahanBakhsh, S.; Soltani, Gh.; ZiyaeiFar, M.

Volume 13, Issue 3 (October 2006) J Birjand Univ Med Sci. 2006, 13(3): 9-15 | Back to browse issues page

Mendeley

Zotero

RefWorks

JahanBakhsh S, Soltani G, ZiyaeiFar M. The effect of dexamethasone on reducing postoperative nausea and vomiting following tonsillectomy. Journals of Birjand University of Medical Sciences 2006; 13 (3) :9-15
URL: http://journal.bums.ac.ir/article-1-98-en.html

The effect of dexamethasone on reducing postoperative nausea and vomiting following tonsillectomy

S. JahanBakhsh ^*¹

, Gh. Soltani²

, M. ZiyaeiFar³

1- Assistant Professor, Department of Anesthesia. Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , ssjahan@mums.ac.ir
2- Assistant Professor, Department of Anesthesia. Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3- Anesthesiologist, Imam Reza Hospital, Birjand University of Medical Sciences, Birjand, Iran

Abstract: (32533 Views)

Background and Aim: Tonsillectomy is one of the most common operations in children. This operation is associated with complications such as nausea and vomiting, pain and dysphagia postoperatively. The aim of this study was to evaluate the effect of a single dose of dexamethasone on the incidence of postoperative nausea and vomiting (PONV). Materials and Methods: In this double-blinded study, 130 patients who had referred to Imam Reza hospital-affiliated to BUMS- for tonsillectomy were randomly divided into case and control groups. The case group was administered dexamethasone 0.5 mg/kg (Maximum dose 25 mg) IV preoperatively. The control group received an equivalent volume of saline preoperatively. Then, the incidence of PONV, time of first oral intake and time of recovery were compared in both groups were compared. The obtained data were statistically analysed at the significant level P≤0.05 by means of statistical software’s SPSS and Chi-square test. Results: Compared with placebo (Saline), dexamethasone significantly decreased the incidence of PONV (P=0.048). The time of first oral intake was shorter (P=0.003) but the time of recovery was not different (P=0.159). Conclusion: Preoperative dexamethasone reduces both PONV and the time of first oral intake without any effect on recovery time.

Keywords: Tonsillectomy, PONV, Dexamethasone

Full-Text [PDF 161 kb] (3022 Downloads)

Type of Study: Original Article | Subject: ENT
Received: 2006/09/6 | Accepted: 2016/03/10 | ePublished: 2016/03/10