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JBUMS 2023, 30(1): 67-78 |
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Bagherpour H, Seghatoleslami M J, AllahResani A, Mousavi G. Assessmentof phytochemical characteristics of two medicinal plants species, Ziziphora tenuir and Teucrium polium, collected from Sarbisheh region. JBUMS 2023; 30 (1) :67-78
URL: http://journal.bums.ac.ir/article-1-3217-en.html
URL: http://journal.bums.ac.ir/article-1-3217-en.html
1- PhD Student in Medicinal and spices and beverage plants, Birjand branch, Islamic Azad University, Birjand, Iran
2- Faculty of Agriculture, Birjand branch, Islamic Azad University, Birjand, Iran ,mjseghat@yahoo.com
3- Department of Chemistry, Faculty of Science, University of Birjand, Birjand, Iran
4- Faculty of Agriculture, Birjand branch, Islamic Azad University, Birjand, Iran
2- Faculty of Agriculture, Birjand branch, Islamic Azad University, Birjand, Iran ,
3- Department of Chemistry, Faculty of Science, University of Birjand, Birjand, Iran
4- Faculty of Agriculture, Birjand branch, Islamic Azad University, Birjand, Iran
Abstract: (510 Views)
Background and Aims: Ziziphora tenuir and Teucrium polium belong to the Labiatae family. So far, 25 and 4 species of Ziziphora tenuir have been reported in the world and Iran, respectively, which are used for novel digestive disorders, common cold, depression, and migraine. A total of 200 species of Teucrium polium have been identified in the world, and 12 species exist in Iran. The historical use of this herb dates back to the time of Hippocrates and Galen. The present study aimed to investigate some of phytochemical characteristics of two medicinal species of Ziziphora tenuir and Teucrium polium in Sarbisheh region of South Khorasan Province.
Materials and Methods: In this in vitro study, the aerial parts of Ziziphora tenuir and Teucrium polium, including leaves, flowers, and flowering branches, were collected from the region at the end of July 2019, and after drying, the samples were distilled using a Clovnjer machine. The identification of the constitutive compounds of the obtained essential oils was performed using GC and GC/MS devices.
Results: The main composition of the essential oil in Ziziphora tenuir in the study area was Pulegone, with 92.55%, including eight types of essential oil composition. The highest amount of effective substances was reported for phenol and antioxidant, while tannin and flavonoid had the lowest amount. 23 essential oil compounds, including Camphor (43.72) and Artemisia alcohol (18.61%) were identified as the highest amounts for Teucrium polium, while Cymene (0.42) and a-Thujone (0.24%) were reported as the lowest amounts. The effective ingredients of Teucrium polium, including Phenol and antioxidant, in contrast with flavonone and flavonoid, were respectively reported as the highest and lowest amounts.
Conclusion: The high amount of Phenol in both species indicated the inhibitory power and is related to the Terpinen compounds in the essential oil of both species. On the other hand, the lower the IC50 value, the higher the inhibition of free radicals and, as a result, the higher the antioxidant property.
*Corresponding Author: Mohammad Javad Seghatoleslami; Emails: mjseghat@yahoo.com
Materials and Methods: In this in vitro study, the aerial parts of Ziziphora tenuir and Teucrium polium, including leaves, flowers, and flowering branches, were collected from the region at the end of July 2019, and after drying, the samples were distilled using a Clovnjer machine. The identification of the constitutive compounds of the obtained essential oils was performed using GC and GC/MS devices.
Results: The main composition of the essential oil in Ziziphora tenuir in the study area was Pulegone, with 92.55%, including eight types of essential oil composition. The highest amount of effective substances was reported for phenol and antioxidant, while tannin and flavonoid had the lowest amount. 23 essential oil compounds, including Camphor (43.72) and Artemisia alcohol (18.61%) were identified as the highest amounts for Teucrium polium, while Cymene (0.42) and a-Thujone (0.24%) were reported as the lowest amounts. The effective ingredients of Teucrium polium, including Phenol and antioxidant, in contrast with flavonone and flavonoid, were respectively reported as the highest and lowest amounts.
Conclusion: The high amount of Phenol in both species indicated the inhibitory power and is related to the Terpinen compounds in the essential oil of both species. On the other hand, the lower the IC50 value, the higher the inhibition of free radicals and, as a result, the higher the antioxidant property.
*Corresponding Author: Mohammad Javad Seghatoleslami; Emails: mjseghat@yahoo.com
You can also search for this author in: PubMed ResearchGate Scopus Google Scholar Google Scholar Profile
Type of Study: Original Article |
Subject:
Medicinal plants
Received: 2022/10/4 | Accepted: 2023/06/13 | ePublished ahead of print: 2023/06/14 | ePublished: 2023/06/5
Received: 2022/10/4 | Accepted: 2023/06/13 | ePublished ahead of print: 2023/06/14 | ePublished: 2023/06/5
References
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2. Kakaei S. and shahbazi Y. Effect of chitosan-gelatin film incorporated with ethanolic red grape seed extract and Ziziphora clinopodioides essential oil on survival of listeria monocytogenes and chemical/ microbial and sensory properties of minced trout fillet. LWT-Food Science and Technology. 2016; 72: 432-38. DOI: 10.1016/j.lwt.2016.05.021
3. Gharibzahedi SMT Mohammadnabi S. Effect of novel bioactive edible coatings based on jujube gum and nettle oil-loaded nanoemulsions on the shelf-life of Beluga sturgeon fillets. International Journal of Biological Macromolecules. 2017; 95: 769-70. DOI: 10.1016/j.ijbiomac.2016.11.119
4. Batooli H, Akhbari M, Hosseinizadeh SMJ. Effect of different distillation methods on quantity and quality of essential oil of two Ziziphora L. Species. J. Med Herb. 2012; 3(3): 135-46. [Persian]. URL: https://jhd.shahrekord.iau.ir/article_633221.html
5. Mozaffarian V. An Encyclopedia of plants, Plant classification. Tehran; Tehran university press. 1994 -750 pp.
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7. Smejkal k, Malanik M, Zhaparkulova k, Sakipova Z Ibragimova L Ibadullaeva G, et al. Kazakh Ziziphora Species as sources of bioactive substances. Molecules. 2016; 21(7): 826. DOI: 10.3390/molecules21070826
8. Soltani-Nejad Sh. Chemical Composition and in vitro antibacterial activity of Ziziphora clinopodioides lam. Essential oil against some pathogenic bacteria. African Journal of Microbiology Research. 2012; 6(7): 1504-8. DOI: 10.5897/AJMR11.1362
9. Masrournia M, Shams AR. Elemental determination and essential oil. Composition of Ziziphora clinopodioides and Consideration of its antibacterial effects. Asian Journal of chemistry. 2013; 25(12): 6553-6. DOI: 10.14233/ajchem.2013.14358
10. Zargari A. Medicinal plants. 4th ed. Tehran university press. Tehran; 1997.Pp: 103-4. https://www.scirp.org/(S(351jmbntvnsjt1aadkposzje))/reference/ReferencesPapers.aspx?ReferenceID=894618
11. Niazmand S, Erfanian Ahmadpoor M, Moosavian M, Derakhshan M. The Positive inotropic and chronotropic effects of Teucrium polium L. extraction Guinea pig isolated heart. Pharmacologyonline. 2008; 2: 588-94. URL: https://pharmacologyonline.silae.it/files/archives/2008/vol2/56_Niazmand.pdf
12. Mahmoudi R, Zare P, Nosratpour S. Application of Teucrium Polium essential oil and Lactobacillus Casein yoghurt.J. Essent. Oil-Bear. Plants. 2015; 18(2): 477-81. DOI: 10.1080/0972060X.2014.935066
13. Amraei M, Ghorbani A, Seifinejad Y, Mousavi S.F, Mohamadpour M,Shirzadpour E. The effect of hydroalcolic extract of Teucrium Polium L. on the inflammatory markers and Lipid Profilein hypercholestrolemic rats. J Inflamm Res. 2018; 11: 265-72. DOI: 10.2147/JIR.S165172
14. Sabzeghabaie A, Asgarpanah J.. Essential Oil Composition of Teucrium. Polium L. fruits. Journal of Essentiol Oil Research. 2016; 28(1): 77-80. DOI: 10.1080/10412905.2015.1082947
15. Adams, R. P. 2007. Identification of essential oil components by gas chromatography/ mass spectrometry, 4th Edition. Allured Publ., Carol Stream, IL Is out of print, but you can obtain a free pdf of it at www.juniperus.org https://books.google.com/books/about/Identification_of_Essential_Oil_Componen.html?id=9ut3PQAACAAJ
16. Adams R.P.. Identification of Essential Oil Components by Gas Chromatography/Mass Spectroscopy/ 4nd edn. Allured Publishing Corporation/ Carol Stream/ Illinois. 2017.
17. Meshaikhi C, Atashi S. Guide to plant physiology tests. Agricultural Education Research. 2016. 317 pp.
18. Miliauskas G,Venskutonis P.R Van Beek T.A. Screening of radical Scavening activity of some medicinal and aromatic plant extracts. Food chemistry. 2004; 85(2): 231-7. DOI: 10.1016/j.foodchem.2003.05.007
19. Krishnaiah D, Devi T, Bono A, Sarbatly R. Studies on phytochemical Constituents of six Malaysian medicinal plants. Journal of Medicinal plants Research. 2009; 3(2): 67-72.
20. Schiegel H.G. Die verwertung organischer sauren durch chlorella in licht. Plata. 1956; 47: 510-15. DOI 10.1007/BF01935418
21. Dehghan Z, Sefidkon F, Emami S.M, Kalvandi R. The effects of ecological factors on essential oil yield and Composition of Ziziphora clinopodioides lam. Subsp. Rigida (Boiss). Rech. F. Journal of plant Researches (Iranian Journal of Biology). 2014; 27(1): 61-71. URL: https://plant.ijbio.ir/article_294.html?lang=en
22. Goulas V, Gomez-Caravaca AM, Exarchou V, Gerothanassis IP, Segura-Carretero A, Gutiérrez AF. Exploring the antioxidant potential of Teucrium polium extracts by HPLCSPE- NMR and on-line radical scavenging activity detection. LWT-Food Science and Technology. 2012; 46(1): 104-9. DOI: 10.1016/j.lwt.2011.10.019
23. Esmaeili MA, Sadeghi H. Pancreatic Β-cell protective effect of rutin and apigenin isolated from Teucrium Polium. Pharmacology online. 2009; 2: 341-53. URL.
24. Shahbazi Y, Shavisi N, Mohebi E. Potential application of Ziziphora Clinopodioides essential oil and niacinas natural preservatives against Bacillus cereus and Escherichia coli O157:H7 in Commercial barley soup. Journal of food safety. 2016; 36(4): 435-41. DOI: 10.1111/jfs.12257
25. Rondeh M, Valizadeh J, Kazemipour N, 2018. Investigation of the essential oil and antioxidant properties of the mountain kakuti plant. National Conference of Medicinal Plants. 45-51. https://www.sid.ir/paper/820623/fa
26. Sadeghi M. and Zarei M.A. 2020. Evaluation of Antioxidant Activity and Determination of Phenol and Flavonoids in Hexane Extract of Aerial Parts of Plants .Descurainia Sophia and Fumaria vaillantii. Plant Research Journal (Iranian Biology Journal). Volume 33, Number 2. pp 384- 395. https://plant.ijbio.ir/article_1531_98136588db7a34844b93c91ec90f621e.pdf
27. Mahdavi S.kh, Asghari P, Mazandarani M, Hosseini S.A, Human B. Evaluation of hypericinin Hypericum. Perforatum L. (Case study: Golestan National park and Ramian). Eco-phytochemical Journal of Medicinal plants. 2013; 1(2): 76-87. [Persian]. URL: https://ecophytochemical.gorgan.iau.ir/article_555365.html
28. Abtahi S.M, Bagherzadeh k. Essential Oil Composition of Teucrium. Polium L. in different ecological conditions (Isfahan province). Eco-phytochemical Journal of Medicinal Plants. 2014; 2(2): 30-8. [Persian]. URL: https://ecophytochemical.gorgan.iau.ir/article_555397_f14301e2757cfc8f5ee8d7aa5c273f67.pdf?lang=en
29. Sadeghi H, Jamalpour S,Shirzadi M.H. Variability in essential oil of Teucrium polium L. of different Latitudinal Populations. Industrial Crops and products. 2014; 54: 130-4. [Persian]. DOI: 10.1016/j.indcrop.2014.01.015
30. Baygan A, Safaiyan Sh, Shahinfar R, Khushkho Zh. Evaluation of antibacterial effect of Ziziphora plant essential oil in North Khorasan region on Gram-negative Salmonella Typhimurium bacteria in vitro. J. Food Sci. Technol.130(19), 355-70. [Persian]. https://fsct.modares.ac.ir/article-7-61678-fa.pdf
31. Sadat-Hosseinia M, Farajpour M, Boroomand N, Solaimani-Sardou F. Ethnopharmacological Studies of indigenous medicinal plants in the south of kerman, Iran. Journal of ethnopharmacology. 2017; 199: 194-206.
33. Smaoui S,Hsouna AB, Lahmar A, Ennouri K, Mtibaa-Chakchouk A, Sellem I, et al. Bio- Preservative effect of the essential oil of the endemic Mentha piperita used alone and in combination with BacTN635 in stored minced beef meat. Meat Science. 2016; 117: 196-204. DOI: 10.1016/j.meatsci.2016.03.006
34. Kakaei S. and shahbazi Y. Effect of chitosan-gelatin film incorporated with ethanolic red grape seed extract and Ziziphora clinopodioides essential oil on survival of listeria monocytogenes and chemical/ microbial and sensory properties of minced trout fillet. LWT-Food Science and Technology. 2016; 72: 432-38. DOI: 10.1016/j.lwt.2016.05.021
35. Gharibzahedi SMT Mohammadnabi S. Effect of novel bioactive edible coatings based on jujube gum and nettle oil-loaded nanoemulsions on the shelf-life of Beluga sturgeon fillets. International Journal of Biological Macromolecules. 2017; 95: 769-70. DOI: 10.1016/j.ijbiomac.2016.11.119
36. Batooli H, Akhbari M, Hosseinizadeh SMJ. Effect of different distillation methods on quantity and quality of essential oil of two Ziziphora L. Species. J. Med Herb. 2012; 3(3): 135-46. [Persian]. URL: https://jhd.shahrekord.iau.ir/article_633221.html
37. Mozaffarian V. An Encyclopedia of plants, Plant classification. Tehran; Tehran university press. 1994 -750 pp.
38. Alp S, Ercisli S, Dogan H, Temin E, Leto A, Zia-UL-Haq M, et al. (2016). Chemical Composition and antioxidant activity Ziziphora clinopodioides ecotypes from Turkey. Romanion Biotechnological Letters. 2016; 21(2): 11298-303. URL: https://www.rombio.eu/rbl2vol21/6_Ercisli.pdf
39. Smejkal k, Malanik M, Zhaparkulova k, Sakipova Z Ibragimova L Ibadullaeva G, et al. Kazakh Ziziphora Species as sources of bioactive substances. Molecules. 2016; 21(7): 826. DOI: 10.3390/molecules21070826
40. Soltani-Nejad Sh. Chemical Composition and in vitro antibacterial activity of Ziziphora clinopodioides lam. Essential oil against some pathogenic bacteria. African Journal of Microbiology Research. 2012; 6(7): 1504-8. DOI: 10.5897/AJMR11.1362
41. Masrournia M, Shams AR. Elemental determination and essential oil. Composition of Ziziphora clinopodioides and Consideration of its antibacterial effects. Asian Journal of chemistry. 2013; 25(12): 6553-6. DOI: 10.14233/ajchem.2013.14358
42. Zargari A. Medicinal plants. 4th ed. Tehran university press. Tehran; 1997.Pp: 103-4. https://www.scirp.org/(S(351jmbntvnsjt1aadkposzje))/reference/ReferencesPapers.aspx?ReferenceID=894618
43. Niazmand S, Erfanian Ahmadpoor M, Moosavian M, Derakhshan M. The Positive inotropic and chronotropic effects of Teucrium polium L. extraction Guinea pig isolated heart. Pharmacologyonline. 2008; 2: 588-94. URL: https://pharmacologyonline.silae.it/files/archives/2008/vol2/56_Niazmand.pdf
44. Mahmoudi R, Zare P, Nosratpour S. Application of Teucrium Polium essential oil and Lactobacillus Casein yoghurt.J. Essent. Oil-Bear. Plants. 2015; 18(2): 477-81. DOI: 10.1080/0972060X.2014.935066
45. Amraei M, Ghorbani A, Seifinejad Y, Mousavi S.F, Mohamadpour M,Shirzadpour E. The effect of hydroalcolic extract of Teucrium Polium L. on the inflammatory markers and Lipid Profilein hypercholestrolemic rats. J Inflamm Res. 2018; 11: 265-72. DOI: 10.2147/JIR.S165172
46. Sabzeghabaie A, Asgarpanah J.. Essential Oil Composition of Teucrium. Polium L. fruits. Journal of Essentiol Oil Research. 2016; 28(1): 77-80. DOI: 10.1080/10412905.2015.1082947
47. Adams, R. P. 2007. Identification of essential oil components by gas chromatography/ mass spectrometry, 4th Edition. Allured Publ., Carol Stream, IL Is out of print, but you can obtain a free pdf of it at www.juniperus.org https://books.google.com/books/about/Identification_of_Essential_Oil_Componen.html?id=9ut3PQAACAAJ
48. Adams R.P. Identification of Essential Oil Components by Gas Chromatography/Mass Spectroscopy/ 4nd edn. Allured Publishing Corporation/ Carol Stream/ Illinois. 2017.
49. Meshaikhi C, Atashi S. Guide to plant physiology tests. Agricultural Education Research. 2016. 317 pp.
50. Miliauskas G,Venskutonis P.R Van Beek T.A. Screening of radical Scavening activity of some medicinal and aromatic plant extracts. Food chemistry. 2004; 85(2): 231-7. DOI: 10.1016/j.foodchem.2003.05.007
51. Krishnaiah D, Devi T, Bono A, Sarbatly R. Studies on phytochemical Constituents of six Malaysian medicinal plants. Journal of Medicinal plants Research. 2009; 3(2): 67-72.
52. Schiegel H.G. Die verwertung organischer sauren durch chlorella in licht. Plata. 1956; 47: 510-15. DOI 10.1007/BF01935418
53. Dehghan Z, Sefidkon F, Emami S.M, Kalvandi R. The effects of ecological factors on essential oil yield and Composition of Ziziphora clinopodioides lam. Subsp. Rigida (Boiss). Rech. F. Journal of plant Researches (Iranian Journal of Biology). 2014; 27(1): 61-71. URL: https://plant.ijbio.ir/article_294.html?lang=en
54. Goulas V, Gomez-Caravaca AM, Exarchou V, Gerothanassis IP, Segura-Carretero A, Gutiérrez AF. Exploring the antioxidant potential of Teucrium polium extracts by HPLCSPE- NMR and on-line radical scavenging activity detection. LWT-Food Science and Technology. 2012; 46(1): 104-9. DOI: 10.1016/j.lwt.2011.10.019
55. Esmaeili MA, Sadeghi H. Pancreatic Β-cell protective effect of rutin and apigenin isolated from Teucrium Polium. Pharmacology online. 2009; 2: 341-53. URL.
56. Shahbazi Y, Shavisi N, Mohebi E. Potential application of Ziziphora Clinopodioides essential oil and niacinas natural preservatives against Bacillus cereus and Escherichia coli O157:H7 in Commercial barley soup. Journal of food safety. 2016; 36(4): 435-41. DOI: 10.1111/jfs.12257
57. Rondeh M, Valizadeh J, Kazemipour N, 2018. Investigation of the essential oil and antioxidant properties of the mountain kakuti plant. National Conference of Medicinal Plants. 45-51. https://www.sid.ir/paper/820623/fa
58. Sadeghi M. and Zarei M.A. 2020. Evaluation of Antioxidant Activity and Determination of Phenol and Flavonoids in Hexane Extract of Aerial Parts of Plants .Descurainia Sophia and Fumaria vaillantii. Plant Research Journal (Iranian Biology Journal). Volume 33, Number 2.pp 384- 395. https://plant.ijbio.ir/article_1531_98136588db7a34844b93c91ec90f621e.pdf
59. Mahdavi S.kh, Asghari P, Mazandarani M, Hosseini S.A, Human B. Evaluation of hypericinin Hypericum. Perforatum L. (Case study: Golestan National park and Ramian). Eco-phytochemical Journal of Medicinal plants. 2013; 1(2): 76-87. [Persian]. URL: https://ecophytochemical.gorgan.iau.ir/article_555365.html
60. Abtahi S.M, Bagherzadeh k. Essential Oil Composition of Teucrium. Polium L. in different ecological conditions (Isfahan province). Eco-phytochemical Journal of Medicinal Plants. 2014; 2(2): 30-8. [Persian]. URL: https://ecophytochemical.gorgan.iau.ir/article_555397_f14301e2757cfc8f5ee8d7aa5c273f67.pdf?lang=en
61. Sadeghi H, Jamalpour S,Shirzadi M.H. Variability in essential oil of Teucrium polium L. of different Latitudinal Populations. Industrial Crops and products. 2014; 54: 130-4. [Persian]. DOI: 10.1016/j.indcrop.2014.01.015
62. Baygan A, Safaiyan Sh, Shahinfar R, Khushkho Zh. Evaluation of antibacterial effect of Ziziphora plant essential oil in North Khorasan region on Gram-negative Salmonella Typhimurium bacteria in vitro. J. Food Sci. Technol.130(19), 355-70. [Persian]. https://fsct.modares.ac.ir/article-7-61678-fa.pdf
63. Sadat-Hosseinia M, Farajpour M, Boroomand N, Solaimani-Sardou F. Ethnopharmacological Studies of indigenous medicinal plants in the south of kerman, Iran. Journal of ethnopharmacology. 2017; 199: 194-206.
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