Journal of Translational Medical Research

Helicobacter pylori (HP) is the most common human pathogen. Due to differences in HP prevalence in different geographical areas, this study was conducted to investigate the seroprevalence of HP in patients with gastrointestinal disorders referring to Imam Reza Hospital in Birjand, Iran, in 2018. After blood sampling of 2,550 patients, the anti-HP antibody titer was measured by a commercial kit. The positive serum response of HP in this study was shown in 1,045 individuals (41%). The results of the present study showed that there was no significant relation between serum positive reaction and gender. In addition, the immunoglobulin G (IgG) antibody with 83% was the most abundant antibody in individuals with positive seropositive reaction. Epidemiological studies, especially serum IgG, can highly help with the detection of HP infection, particularly in individuals with clinical symptoms (P<0.05).