Sayed Damoon Sadoughi, Raheleh Rahbarian,
Volume 24, Issue 0 (Supplementary- Biochimistry & Metabolism) 2017)
Abstract
Background and Aim: Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder, which is characterized by ovulatory dysfunction and hyperandrogenism. Regarding to the antioxidant properties of green tea (Camellia sinensis) compounds, the present study was done to evaluate the effect of aqueous extract of green tea and catechin on the status of sex hormones and ovaries in polycystic ovarian syndrome rat model.
Materials and Methods: In this experimental study, 42 Wistar female rats were divided into 7 equal groups of control, PCOS control, PCOS treated with aqueous extract of green tea (50 and 100 mg/kg, 24 days, ip), PCOS treated with catechin (50 and 100 mg/kg, 24 days, ip) and PCOS treated with clomiphene citrate (1.5 mg/kg, 24 days, ip). Polycystic ovarian syndrome was induced by a single intramuscular injection of estradiol valerate (4 mg/kg). At the end of administration period, serum level of LH, FSH, β-estradiol, Progesterone, and testosterone was measured using ELISA. Also, the number of ovarian follicles was counted. The obtained data was analyzed using one-way ANOVA and Post Hoc Tukey statistical tests.
Results: Compared to PCOS control group, serum level of LH, β-estradiol, testosterone and number of cystic follicles in the groups treated with clomiphene citrate, treated with 100 mg/kg aqueous extract of green tea and treated with 50 and 100 mg/kg of catechin significantly decreased, but serum level of FSH, progesterone and number of preantral, antral, preovulatory follicles, and corpus luteum significantly increased (p<0.05).
Conclusion: Compared with green tea, catechin has a more favorable effect on improving hormonal parameters, especially FSH hormone and increasing the number of ovarian follicles in rats with polycystic ovary syndrome.
Farzaneh Mirhoseini, Mahdi Tabrizizadeh, Azadeh Falah-Yakhdani, Amin Ansarinia, Monireh Sadoughi,
Volume 26, Issue 1 (Spring 2019)
Abstract
Background and Aim: Intra-bone lesions are common in lesions, among them periapical lesions have a higher incidence. Todays, all direct digital imaging systems provide various types of image processing techniques. The purpose of this study is to investigate the effects of different digital image processing techniques on the diagnosis of bony defects.
Materials and Methods: In this experimental study, 50 sheep inferior half-jawbones were used. Lesions were created by round bars with numbers 1/4, 1/2, 1, 2 and 4. Digital images were obtained by edge enhance, sharpening, invert gray scale processing method and unprocessed investigated by two radiologists and in case of disagreement them observers by third observer. The method of recording the results was definitive diagnosis of lesion number 1, misdiagnosis number 2 and possible diagnosis number 3 .The results were analyzed by chi-square and Fisher's exact tests.
Results: Percent of diagnostic sensitivity in unprocessed Images (71.8%) and images processed with Sharpen filter (71.4%) were significantly higher than images processed with invert grayscale (68.5%) and edge Enhancer (53%).(p<0.001)
Conclusion: To detect bone lesions, unprocessed and processed digital images with Sharpen filters have higher diagnostic accuracy.