Search published articles


Showing 4 results for Balali Mood

M. Balali Mood, K. Balali Mood, Gh. Danei, E. Ghaeninejad,
Volume 13, Issue 3 (October 2006)
Abstract

Introduction: Organophosphorous (OP) chemical warfare nerve agents are similar to OP pesticides in their structure and toxic mechanisms.. These agents mainly sarin and tabun were used during Iran-Iraq war with high mortalities. Sarin was also used as chemical terrorism in Matsomoto and Tokyo metro in 1994 and 1995, respectively with high morbidity and mortality. Since these lethal agents are still a big threat, medical and even paramedical and nursing staff should obtain enough knowledge about chemical toxicity and be prepared to manage in any chemical events of nerve agents exposure.
Toxicity: OP nerve agents are cholinesterase inhibitors, leading to acetylcholine accumulation at nerve endings, stimulating muscarinic and nicotinic receptors. These agents have also direct effects on CNS and to a lesser degree on cardiovascular system. The toxic effects induce manifestations on different systems including nervous, cardiovascular, and gastrointestinal system and organs such as skin, eyes and skeletal muscles leading to death in severely intoxicated patients.
Management: In addition to atropine and oximes as known antidotes, based on research in Mashhad poisons centre, cheap available pharmaceuticals including sodium bicarbonate, magnesium sulfate, and antioxidants (vitamins C and E) have recently been used successfully for the treatment of OP poisoning. Conclusion: Chemical warfare nerve agents are highly toxic, and induce high morbidity and mortality in chemical wars and terrorism. Thus, prompt emergency and proper management are required. Medical, paramedical and nursing staff must be aware of and be prepared for any possible chemical nerve agents accidents. Sodium bicarbonate, Magnesium sulfate and the antioxidants should be added to the standard treatment of OP poisonings.

Smj. Mortazavi, E. Daiee, M. Ghasemi, M. Balali Mood,
Volume 15, Issue 2 (July 2008)
Abstract

Background and Aim: Mercury or Hydrargyrum (Hg) is the most non-radioactive toxic element known. Dental amalgam is made up of 50% mercury.. Electromagnetic fields may increase the emission of mercury from dental amalgam fillings. It was thus aimed to study the effects of electromagnetic fields of mobile use on the level of mercury released from dental amalgam restorations. Materials and Methods: In this case control clinical trial, study urinary mercury concentrations of 14 healthy University students were measured both before amalgam restoration (zero level), and on days 1, 2, 3 and 4 after restoration. All the subjects had the same diet. Dental treatment was given for all 14 students regarding 2 molars on one side (i.e the side of cellphone exposure), one class I and one class II restorations with identical volume and surface area of the amalgam fillings). All the students had not used mobile phones before the study and did not have any previous amalgam restorations. The test group consisting of seven female students were exposed to microwave radiation emitted from a Nokia 3310 mobile phone (SAR=0.96 W kg-1) that was in talk mode for 15 minutes on days 1-4 after restoration. Seven other female students who had the same condition matched the first group except exposure to microwave radiation were taken as the controls. Urine samples were collected 1 hour after each mobile use (real exposure) and one hour without mobile use (false exposure). After freezing, the samples were sent to the Toxicology Laboratory of Imam Reza Hospital (Mashhad, Iran) and mercury levels in samples were measured by cold vapor atomic absorption spectrometry. The obtained data was analysed by means of a statistical software (SPSS version 13.0) and statistical tests of ANOVA and Student-t at the significant level of P≤0.05. Results: Our study demonstrated an elevation of mercury level released from dental amalgam fillings after exposure to microwave radiation emitted form mobile phones. Mean (±SE) concentration levels of mercury in urine samples in the case group were 2.43±0.25, 2.71±0.27, 3.79±0.25, 4.8± 0.27 and 4.5±0.32 g/L one day before the amalgam restoration and on days 1, 2, 3 and 4, respectively. But mean Hg concentration levels in controls were 2.07±0.22, 2.34±0.30, 2.51±0.25, 2.66± 0.24 and 2.76±0.32 g/L on the respective days. Conclusion: Results obtained from this study show a significant increase of the mercury release in urine after mobile phone use. This finding confirms early reports that showed an increased release of mercury from dental amalgam restorations in undersea welding.
K. Deldar, E. Nazemi, M. Balali Mood, Sa. Emami, Ah. Mohammadpour, M. Tafaghodi, R. Afshari,
Volume 15, Issue 3 (October 2008)
Abstract

Background and Aim: Lead (Pb) poisoning is the most common occupational poisoning that may affect family members of lead workers specially their children. The most important and irreversible effect of lead poisoning in children is on the developing of central nervous system and its evolution. High cost and severe side effects of chelating agents may result in incomplete treatment of lead poisoning in some cases. The aim of the present study was to assess the effect of Coriandrum Sativum l. (Cilantro) extracts on renal lead excretion in 3-7 year old children. Materials and Methods: In this randomized, case–control clinical trial, 32 children aged 3-7 years whose parents were lead-exposed workers were randomly divided into 2 groups. The test group received Cilantro extract and the controls were given placebos for 14 days. Blood and urine lead concentrations were determined at the beginning of the study and 14 days later. Questionnaires were designed and used for data collection. The obtained data were analyzed by T-student and Paired t-test using SPSS version 11.5 Numerical data were shown as mean ± SD and P≤0.05 was taken as the significant level. Results: Mean age and weight of the children was 4.9±1.46 years and 17.32±4.74 kg respectively and 59.4% of them were males. Duration of fathers' exposure to Pb at work was 9.14±5.63 years. Blood and urine Pb concentrations and renal lead clearance of children were 163.81±57.19, 97±48.12 µg/L and .012±.009 L/day, respectively at the beginning of the study. There were no significant differences in blood (P=0.87), urine (P=0.73) Pb concentrations and renal excretion of lead (P=0.96) between the two groups. After two weeks use of Cilantro, the mean blood lead concentration decreased (P=0.006), urine lead concentration increased (P=0.038) and renal excretion of lead increased significantly (P=0.019). But similar significant changes were observed in the control group (P=0.034, 0.021 and 0.009, respectively). There were no significant differences in blood lead concentration (P=0.93), urine lead concentration (P=0.93) and renal lead clearance (P=0.77) between the two groups at the end of the study. Conclusion: According to the results of this study, it seems that Coriandrum Sativum is not effective in lead elimination. Increasing renal lead elimination in both groups of children may be due to other factors like improvement of nutrition following the necessary educations at the beginning of this study.

M.r. Keramati, M. Nemai Ghasemi, M. Balali Mood,
Volume 16, Issue 1 (April 2009)
Abstract

Background and Aim: Iron deficiency anemia is the most common nutritional anemia in developed and developing countries. In addition, lead intoxication especially in developing countries is an increasing risk for health because of rapid urbanization and consumption of leaded fuels. Many studies, particularly on children, have showed a correlation between iron deficiency and increase in blood lead-concentration. In this study, we evaluated this association in workers of a car battery manufacturer. Materials and Methods: This research was performed on workers who were exposed to lead in a car battery manufacturer in Mashhad, Iran, in 2006. Various laboratory tests including complete blood count (CBC), serum ferritin concentration applying radioimmunoassay method and blood lead concentration (BLC) by means of atomic absorption spectrophoyometry) Perkin Elemer, Model 3030) were performed. The obtained data was analyzed by the statistical package for social sciences (SPSS, version 11.5) and statistical tests including t- test and Pearson's correlation coefficient were used. P<0.05 was taken as the significant level. Results: Based on clinical (lead line) and laboratory observations, all workers had lead intoxication with mean BLC of 32.2±13.7 µg/dl. There was not a significant difference between mean BLC in iron-deficient (n=11) and non-iron-deficient workers (n=78). Besides, applying Pearson's correlation coefficient did not reveal any correlation between blood lead with serum ferritin and blood hemoglobin. (r=0.18, P=0.09 and r=0.051, P=0.68 respectively) Conclusion: In this study, no correlation between blood lead concentration with serum ferritin and hemoglobin were observed. Thus, the following are recommended: 1. A similar research in a larger population having longer exposure to lead should be carried out. 2. Health improvement of work environment must be taken into account for the prevention of lead intoxication.

Page 1 from 1     

© 2025 CC BY-NC 4.0 | Journal of Translational Medical Research

Designed & Developed by : Yektaweb