Background and Aim: Dialysis patients are prone to various complications such as physical, economic, social and psychological problems which can result in psychopathological complications.. The current study aimed at assessing the effectiveness of psychological rehabilitation using Dohsa-Hou, on reducing ESRD (Hemodialysis) patients’ depression, anxiety, and stress, in Zahdan city.

Materials and Methods: The present study is a semi experimental research on 30 patients of hemodialysis (ESRD) men, having medical records in Kidney Patient Support Foundation and Private Centers of Zahdan city. These  patients were selected through available sampling method. They were randomly divided into two equal groups: experimental  and control group.). The experimental group underwent 11 therapy sessions Dohsa psychomotor relaxation for 11 weeks, each lasting 45 minutes. Data collection tool was depression, anxiety, and stress questionnaire (DASS-21). The obtained data was analyzed by means of SPSS software (V:19), applying independent t-test and covariance statistical tests.

Results: Mean score of depression, anxiety, and stress in the experimental and control   groups, revealed no significant difference before intervention (P>0.05), but it was significantly lower in the experimental group compared to the control (P<0.001). Moreover, after intervention, the mean in the mentioned domains significantly decreased compared to their previous levels (P<0.001). However, in the control group no significant difference was found (P>0.05).

Conclusion: The results showed that psychological rehabilitation using Dohsa-Hou has a significant impact on reducing ESRD patients’ depression, anxiety, and stress. Therefore, not only prescribing medicines for their problems is suggested, but also. psychologic interventions are recommended.