@ARTICLE{Eizadi, author = {Eizadi, Mojtaba and Kazemzade, Yaser and Behbudi, Laleh and Banaeifar, Abdolali and }, title = {Determination of serum adiponectin relationship with insulin resistance in type 2 diabetics}, volume = {20}, number = {4}, abstract ={Background and Aim: Obesity is associated with some chronic morbidity including atherosclerosis, hypertension, and type 2 diabetes which are major components of metabolic syndrome. In the present study, association between insulin resistance and adiponectin, as an anti-inflammatory cytokine, in type 2 obese male diabetics was assessed. Materials and Methods: In this descriptive study, fasting serum adiponectin, insulin, glucose and insulin resistance were measured in 42 obese male type 2 diabetics (aged 37 - 53 years, weight 80-100kg, 30≤BMI≤36). Pearson’s correlation method was used to determine the association between adiponectin levels with insulin resistance, glucose, and insulin in the cases (P≤0.05). Results: Pearson’s correlation method showed a significant negative association between serum adiponectin andinsulin resistance (P=0.000(. Besides, a significant correlation was observed between adiponectin level and fasting glucose (P=0.005). But, no correlation was found between serum adiponectin and insulin (P=0.196). Conclusion: The current study demonstrated that serum adiponectin level, as an anti-inflammation and anti-diabetic cytokine, is a predictive factor of insulin resistance in type 2 diabetics. }, URL = {http://journal.bums.ac.ir/article-1-1249-en.html}, eprint = {http://journal.bums.ac.ir/article-1-1249-en.pdf}, journal = {Journal of Birjand University of Medical Sciences}, doi = {}, year = {2013} }