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balaghi inaloo F, abolfathi F, shabani M, alizadeh A A. The effect of four weeks aerobic training on serum levels of irisin and insulin resistance in women with type II diabetes. J Birjand Univ Med Sci.. 2017; 24
URL: http://journal.bums.ac.ir/article-1-2249-en.html

1- Department of Exercise Physiology, Shahid Chamran University of Ahvaz, Ahvaz, Iran. , faranakbalaghi70@gmail.com
2- Young Researchers and Elite Club, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.
3- Department of Exercise Physiology, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Abstract:   (68 Views)

Background and Aim: physical activities is appropriate a cost-effective means for the prevention and treatment a disease of type II diabetes. Irisin, a recently identified myokine that seems had important role in transformation of white fat tissue and sets insulin sensitivity. The aim of this study was to investigate the effect of aerobic training on serum levels of irisin and insulin resistance in women with type II diabetes.

Materials and Methods: In thia semi experimental study, 24 women with type II diabetes purposefully selected and randomly assigned into two groups aerobic training and control. exercise Group for 4 weeks (5 times a week) run to aerobic workouts 55-80 percent of maximum heart rate intensity on the treadmill. The control group did not any physical activity. Blood samples were done before and 48 hours after the last training session and serum levels irisin of glucose and insulin were used. Data were analyzed using paired t-test, covariance and pearson correlation. The significance level P was considered P<0/05.

Results: The Results showed significant increase in the irisin and reduce in insulin resistance and glucose in exercise group compared with the control group (P<0/05) the difference between the two groups was significant in the irisin and glucose (P<0/05). also There is no significant correlation between  irisin and insulin resistance (P<0/05).

Conclusion: Aerobic exercise through a favorable impact on irisin levels and insulin resistance, is complications to improve operating efficiency in patients with type II diabetes.

     
Type of Study: Original Article | Subject: Biochemistry
Received: 2017/02/18 | Accepted: 2017/04/23 | Published: 2017/06/13

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