Volume 20, Number 1 (April 2013)                   J Birjand Univ Med Sci. 2013, 20(1): 94-101 | Back to browse issues page


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Ghavami Ghanbarabadi V, Jamali J, Heidari-Bakavoli A, Tayyebi M, Nazari Hyanlo H, Shakeri M T. Factors influencing the status of appropriate and inappropriate shocks delivered by an implantable cardioverter defibrillator. J Birjand Univ Med Sci.. 2013; 20 (1) :94-101
URL: http://journal.bums.ac.ir/article-1-1242-en.html

1- PhD Student in Biostatistics Department of Biostatistics, School of Health, Tehran University of Medical Sciences, Tehran, Iran
2- PhD Student in Biostatistics Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3- Assistant Professor Department of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- MD Mashhad University of Medical Sciences, Mashhad University of Medical Science, Mashhad, Iran
5- Associate Professor Department of Biostatistics, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran , shakerimt@mums.ac.ir
Abstract:   (7609 Views)
 Background and Aim: The QRS duration is a strong predictor of mortality, particularly in heart failure patients. However, studies on the usefulness of QRS duration, as a predictor of ventricular arrhythmic events in ICD patients, have proved to be contradictory. Since in patients with implantable cardioverter defibrillator (ICD), all of the malignant ventricular arrhythmias are recorded and treated with appropriate shock (i.e. appropriate shock and inappropriate shock), in the present study the relationship between the QRS duration and status of appropriate or inappropriate ICD shocks was evaluated. 

Materials and Methods: In this cross-sectional study 65 patients with implanted cardioverter defibrillator were included to prevent their undue death. Before the implantation, QRS duration in the surface ECG was measured and recorded. Furthermore, variables such as age, gender, indication for ICD implantation, family history of sudden cardiac death, and QTc interval before ICD implantation were recorded. During follow-up visits of the patients, ICDs were interrogated and appropriate and inappropriate therapies were traced. Finally logistic regression in SPSS statistical software (V: 11.5) was used for data analysis.

 Results: Mean age of the patients was 17.208±47.92 years. Eighteen patients (27.7%) were females and 58 (89.2%) had a family history of sudden cardiac death. Mean QRS duration and QTc interval were 36.78 ± 117.94 msec and 62.42±466.97 msec, respectively. There was no statistically significant relationship between QRS duration and status of appropriate and inappropriate ICD shocks. Among the studied parameters, there was only a significant relationship between status of appropriate or inappropriate ICD shocks and the different manufacturers of ICD devices.  

Conclusion: QRS duration does not have a significant relationship with status of appropriate and inappropriate ICD shocks. This may not predict arrhythmic events in ICD patients. 

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Subject: Cardiology
Received: 2012/09/17 | Accepted: 2013/05/14 | Published: 2016/03/10

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